Evidence map›Paper›PMID 29229929›Full record

ArticleScientific reports2017

Oestrogen Receptor-α binds the FOXP3 promoter and modulates regulatory T-cell function in human cervical cancer.

Sreenivas Adurthi, Mahesh M Kumar, H S Vinodkumar, Geetashree Mukherjee, H Krishnamurthy, K Kshitish Acharya, U D Bafna, Devi K Uma, B Abhishekh, Sudhir Krishna and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
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  5. The HIV Reservoir and Immune Landscape Across the Life Course of Women: Implications for Cure Strategies.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026
    Review
  6. Article
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  9. Overcoming resistance to anti-PD-1/PD-L1 therapy in cancer.Cancer drug resistance (Alhambra, Calif.) · 2026
    Review
  10. Cervicovaginal microbiome alterations across HPV infection.Frontiers in cellular and infection microbiology · 2026
    Article
  11. Review
  12. Sex as a modifier of genetic risk for type 1 diabetes.Diabetes, obesity & metabolism · 2025
    Review
  13. Review
  14. Review
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Sreenivas AdurthiDepartment of Microbiology, Kidwai Memorial Institute of Oncology, Bangalore, India.
Mahesh M KumarDepartment of Microbiology, Kidwai Memorial Institute of Oncology, Bangalore, India.
H S VinodkumarShodhaka Life Sciences Private Limited, Bangalore, India.
Geetashree MukherjeeDepartment of Pathology, Kidwai Memorial Institute of Oncology, Bangalore, India.
H KrishnamurthyNational Center for Biological Sciences, TIFR, Bangalore, India.
K Kshitish AcharyaShodhaka Life Sciences Private Limited, Bangalore, India.
U D BafnaDepartment of Gynecology, Kidwai Memorial Institute of Oncology, Bangalore, India.
Devi K UmaDepartment of Gynecology, Kidwai Memorial Institute of Oncology, Bangalore, India.
B AbhishekhDepartment of Immunohematology, Kidwai Memorial Institute of Oncology, Bangalore, India.
Sudhir KrishnaNational Center for Biological Sciences, TIFR, Bangalore, India.
A ParchureDepartment of Microbiology, Kidwai Memorial Institute of Oncology, Bangalore, India.
Murali AlkaDepartment of Microbiology, Kidwai Memorial Institute of Oncology, Bangalore, India.
R S JayshreeDepartment of Microbiology, Kidwai Memorial Institute of Oncology, Bangalore, India. microjayshree@gmail.com.ORCID 0000-0002-7872-8726
Kidwai Memorial Institute of Oncology · INNational Centre for Biological Sciences · INInstitute of Bioinformatics and Applied Biotechnology · INVellore Institute of Technology University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oestrogen controls Foxp3 expression in regulatory T cells (T

Indexed as

Promoter Regions, GeneticResponse ElementsCarcinoma, Squamous CellEstradiolEstrogen Receptor alphaEstrogensFemaleForkhead Transcription FactorsGene Expression Regulation, NeoplasticHumansSignal TransductionT-Lymphocytes, RegulatoryTumor Cells, CulturedUterine Cervical NeoplasmsESR1 protein, humanEstradiolEstrogen Receptor alphaEstrogensForkhead Transcription FactorsFOXP3 protein, human

Identifiers

PMID29229929
PMCPMC5725534
OpenAlexW2772987964

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.