ArticleAnnals of Saudi medicine
Prognostic factors for epilepsy following first febrile seizure in Saudi children.
Article in Annals of Saudi medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- The baseline risk of multiple febrile seizures in the same febrile illness: a meta-analysis.European journal of pediatrics · 2022Pooled it
- Febrile Seizures in Children in a Low-Resource Setting: A Hospital-Based Cross-Sectional Study from Eastern Libya.Avicenna journal of medicine · 2026Article
- Anthropogenetic Variability in the Group of Individuals with Febrile Seizures: Population-Genetic Study.BioMed research international · 2018Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFebrile seizure is the most common convulsive event during childhood, but it is generally considered benign.
objectivesTo estimate the rate of epilepsy after first presentation of febrile seizure and to describe factors that can predispose children to have subsequent epilepsy after their first febrile seizure.
designRetrospective chart review.
settingA tertiary care center in Riyadh. PATIENTS AND
methodsAll children whose first febrile seizure developed between 2009-2012, and who were admitted to the pediatric wards.
main outcome measuresThe rate of epilepsy and prognostic factors for epilepsy following first febrile seizure.
resultsOf 109 febrile seizure patients, 6 (5.5%, 95% CI: 2.1% - 11.6%) were diagnosed with subsequent epilepsy 5 to 46 months after their first febrile seizure. The risk of having subsequent epilepsy was higher in children who were convulsing at a low-grade fever during their first febrile convulsion (P=.02). Moreover, delayed vaccination status (P=.03), prolonged duration of the first convulsion (P=.04), frequent febrile seizures (P=.01), and fever without documented infection (P=.03) during the first febrile convulsion were associated with epilepsy.
conclusionThe rate of epilepsy following first febrile seizure in Saudi children is within the range of values reported in different populations. Although most childhood febrile seizures are self-limiting, careful observation is needed, particularly for children who exhibit factors associated with epilepsy. LIMITATIONS: Conducted at a single center in Saudi Arabia, which may limit generalizability.
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