Evidence map›Paper›PMID 29229864›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Cytoplasmic Cl

Mu He, Wenlei Ye, Won-Jing Wang, Eirish S Sison, Yuh Nung Jan, Lily Yeh Jan

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
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  8. Article
  9. TMEM16A drives renal cyst growth by augmenting CaJournal of molecular medicine (Berlin, Germany) · 2020
    Article
  10. Article
  11. Review
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  13. Article
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  15. TMEM16A controls EGF-induced calcium signaling implicated in pancreatic cancer prognosis.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  16. Article
  17. Article
  18. Review
  19. The TMEM16A channel mediates the fast polyspermy block inThe Journal of general physiology · 2018
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Mu HeDepartment of Physiology, University of California, San Francisco, CA 94158.
Wenlei YeDepartment of Physiology, University of California, San Francisco, CA 94158.ORCID 0000-0002-4694-1493
Won-Jing WangInstitute of Biochemistry and Molecular Biology, College of Life Sciences, National Yang-Ming University, Taipei, 11221, Taiwan.
Eirish S SisonDepartment of Physiology, University of California, San Francisco, CA 94158.
Yuh Nung JanDepartment of Physiology, University of California, San Francisco, CA 94158.
Lily Yeh JanDepartment of Physiology, University of California, San Francisco, CA 94158; Lily.Jan@ucsf.edu.
Howard Hughes Medical Institute · USUniversity of California, San Francisco · USNational Yang Ming Chiao Tung University · TW

Funding

Molecular, Genetic & Physiological Studies of Calcium-activated Chloride ChannelsR01NS069229 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JAN, LILY Y · 2011 to 2020
$3.5M
Ion channels as mechanic modulators of epithelial tissue homeostasisF32HD089639 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HE, MU · 2017 to 2019
$190k
Howard Hughes Medical InstituteNICHD NIH HHS F32 HD089639NINDS NIH HHS R01 NS069229
6 · The paper itself

Abstract

Chloride is the major free anion in the extracellular space (>100 mM) and within the cytoplasm in eukaryotes (10 ∼ 20 mM). Cytoplasmic Cl

Indexed as

Adherens JunctionsAnimalsAnoctamin-1Cell MembraneChloridesCiliaEpitheliumIon TransportMiceMorphogenesisPhosphatidylinositol 4,5-DiphosphateANO1 protein, mouseAnoctamin-1ChloridesPhosphatidylinositol 4,5-Diphosphatecalcium-activated chloride channelepithelial morphogenesismembrane remodelingphosphoinositideprimary cilia

Identifiers

PMID29229864
PMCPMC5748203
OpenAlexW2773131752

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.