Evidence map›Paper›PMID 29229849›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Obligatory role of hypothalamic neuroestradiol during the estrogen-induced LH surge in female ovariectomized rhesus monkeys.

Brian P Kenealy, Kim L Keen, James P Garcia, Lucille K Kohlenberg, Ei Terasawa

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 35 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Brain-derived estrogen and neural function.Neuroscience and biobehavioral reviews · 2022
    Review
  10. Sexually Dimorphic Neurosteroid Synthesis Regulates Neuronal Activity in the Murine Brain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  11. Article
  12. Deficiency of arcuate nucleus kisspeptin results in postpubertal central hypogonadism.American journal of physiology. Endocrinology and metabolism · 2021
    Article
  13. Aromatase in the Human Brain.Androgens: clinical research and therapeutics · 2021
    Review
  14. Editorial: Hormone release patterns in mammals.Molecular and cellular endocrinology · 2020
    Article
  15. KNDy Cells Revisited.Endocrinology · 2018
    Review
  16. Review
  17. Review
  18. The 3Journal of neuroendocrinology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Brian P KenealyWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715.
Kim L KeenWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715.
James P GarciaWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715.
Lucille K KohlenbergWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715.
Ei TerasawaWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715; terasawa@primate.wisc.edu.ORCID 0000-0003-3995-6643
University of Wisconsin–Madison · US

Funding

WNPRC Supplemental Request for Nonhuman Primate Enclosures to Equip HIV/AIDS-Related Research FacilitiesP51OD011106 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Dorota A. Grejner-Brzezinska · 2012 to 2026
$150.7M
HYPOTHALAMIC CONTROL OF GONADOTROPIN SECRETIONR01HD015433 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI TERASAWA-GRILLEY, EI · 1985 to 2011
$3.2M
Endocrinology-Reproductive Physiology Training GrantT32HD041921 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI BIRD, IAN M. · 2004 to 2022
$3.0M
Role of neuroestradiol in regulation of the GnRH surgeR01HD089495 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI TERASAWA-GRILLEY, EI · 2018 to 2022
$2.1M
NICHD NIH HHS R01 HD015433NICHD NIH HHS R01 HD089495NICHD NIH HHS T32 HD041921NIH HHS P51 OD011106
6 · The paper itself

Abstract

Negative and positive feedback effects of ovarian 17β-estradiol (E

Indexed as

OvariectomyAnimalsEstradiolEstrogensFemaleGonadotropin-Releasing HormoneHypothalamo-Hypophyseal SystemLuteinizing HormoneMacaca mulattaEstradiolEstrogensGonadotropin-Releasing HormoneLuteinizing HormonearomataseGnRHkisspeptinneuroestradiolpreovulatory surge

Identifiers

PMID29229849
PMCPMC5748216
OpenAlexW2775020980

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.