Evidence map›Paper›PMID 29229824›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Molecular mechanism for the subversion of the retromer coat by the

Miguel Romano-Moreno, Adriana L Rojas, Chad D Williamson, David C Gershlick, María Lucas, Michail N Isupov, Juan S Bonifacino, Matthias P Machner, Aitor Hierro

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Molecular evolution and adaptations ofFrontiers in cellular and infection microbiology · 2026
    Review
  4. Identification of a VPS29 isoform with restricted association to Retriever and Retromer accessory proteins through autoinhibition.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Journal of bacteriology · 2024
    Review
  7. Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27-Retromer complex.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. The Sde phosphoribosyl-linked ubiquitin transferases protect theProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  9. Article
  10. Eat or Be Eaten: Strategies Used byInfection and immunity · 2023
    Review
  11. The Sde Phosphoribosyl-Linked Ubiquitin Transferases protect thebioRxiv : the preprint server for biology · 2023
    Article
  12. Receptor Recycling by Retromer.Molecular and cellular biology · 2023
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Frontiers in cell and developmental biology · 2021
    Review
  19. Targeting Endosomal Recycling Pathways by Bacterial and Viral Pathogens.Frontiers in cell and developmental biology · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Miguel Romano-MorenoStructural Biology Unit, Centro de Investigación Cooperativa en Biociencias, 48160 Derio, Spain.
Adriana L RojasStructural Biology Unit, Centro de Investigación Cooperativa en Biociencias, 48160 Derio, Spain.
Chad D WilliamsonCell Biology and Neurobiology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892.
David C GershlickCell Biology and Neurobiology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0002-0602-210X
María LucasStructural Biology Unit, Centro de Investigación Cooperativa en Biociencias, 48160 Derio, Spain.
Michail N IsupovThe Henry Wellcome Building for Biocatalysis, Biosciences, University of Exeter, Exeter EX4 4SB, United Kingdom.
Juan S BonifacinoCell Biology and Neurobiology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892.
Matthias P MachnerDivision of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892; machnerm@mail.nih.gov ahierro@cicbiogune.es.
Aitor HierroStructural Biology Unit, Centro de Investigación Cooperativa en Biociencias, 48160 Derio, Spain; machnerm@mail.nih.gov ahierro@cicbiogune.es.
National Institutes of Health · USCIC bioGUNE · ESIkerbasque · ESUniversity of Exeter · GB

Funding

Protein Trafficking In The Endosomal-Lysosomal SystemZIAHD001607 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI BONIFACINO, JUAN · 2009 to 2025
$48.3M
Virulence strategies of the respiratory pathogen Legionella pneumophilaZIAHD008893 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI MACHNER, MATTHIAS · 2010 to 2025
$19.6M
Intramural NIH HHS ZIA HD001607Intramural NIH HHS ZIA HD008893
6 · The paper itself

Abstract

Microbial pathogens employ sophisticated virulence strategies to cause infections in humans. The intracellular pathogen

Indexed as

Protein MultimerizationBacterial ProteinsLegionella pneumophilaProtein DomainsProtein Structure, QuaternaryProtein Structure, SecondaryVesicular Transport ProteinsVirulence FactorsBacterial ProteinsVesicular Transport ProteinsVirulence FactorsVPS29 protein, humancoat complexLegionella effectormembrane targetingpathogenic bacteriaX-ray crystallography

Identifiers

PMID29229824
PMCPMC5748213
OpenAlexW2773234794

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.