Evidence map›Paper›PMID 29229734›Full record

ArticleInfection and immunity2018

Macrophage Polarization Alters Postphagocytosis Survivability of the Commensal Streptococcus gordonii.

Andrew J Croft, Sarah Metcalfe, Kiyonobu Honma, Jason G Kay

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  3. Review
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  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. The Regulatory Effect of Coaggregation BetweenFrontiers in cellular and infection microbiology · 2022
    Article
  13. Article
  14. Article
  15. Interactions BetweenFrontiers in cellular and infection microbiology · 2021
    Article
  16. Review
  17. Bacteria ModifymSphere · 2020
    Article
  18. Article
  19. Danger signals in oral cavity-related diseases.Journal of leukocyte biology · 2019
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Andrew J CroftDepartment of Oral Biology, School of Dental Medicine, University at Buffalo, State University of New York, Buffalo, New York, USA.
Sarah MetcalfeDepartment of Oral Biology, School of Dental Medicine, University at Buffalo, State University of New York, Buffalo, New York, USA.
Kiyonobu HonmaDepartment of Oral Biology, School of Dental Medicine, University at Buffalo, State University of New York, Buffalo, New York, USA.
Jason G KayDepartment of Oral Biology, School of Dental Medicine, University at Buffalo, State University of New York, Buffalo, New York, USA jasonkay@buffalo.edu.
University at Buffalo, State University of New York · US

Funding

Advanced Training in Oral BiologyT32DE023526 · NIDCR · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI Stefan Hans-Klaus Ruhl · 2013 to 2026
$3.7M
Mechanisms of Streptococcus gordonii survival within phagocytesR03DE025062 · NIDCR · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI KAY, JASON G · 2016 to 2017
$239k
NIDCR NIH HHS R03 DE025062NIDCR NIH HHS T32 DE023526
6 · The paper itself

Abstract

Oral streptococci are generally considered commensal organisms; however, they are becoming recognized as important associate pathogens during the development of periodontal disease as well as being associated with several systemic diseases, including as a causative agent of infective endocarditis. An important virulence determinant of these bacteria is an ability to evade destruction by phagocytic cells, yet how this subversion occurs is mostly unknown. Using

Indexed as

Cell PolarityAnimalsBacterial ProteinsHumansMacrophagesMicePhagosomesRAW 264.7 CellsReactive Oxygen SpeciesStreptococcal InfectionsStreptococcus gordoniiBacterial ProteinsReactive Oxygen Speciesmacrophagesoral microbiologyphagocytosis

Identifiers

PMID29229734
PMCPMC5820930
OpenAlexW2771976497

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.