ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018
A Unifying Motif for Spatial and Directional Surround Suppression.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Astrocyte Autophagy in Neurodegenerative Diseases: Current Progress in Mechanisms and Therapeutics.Neurochemical research · 2025Review
- Behavioral state and stimulus strength regulate the role of somatostatin interneurons in stabilizing network activity.Cell reports · 2025Article
- Directional Motion Sensitivity in Visual Snow Syndrome and Its Relation to Trailing-Type Palinopsia.Investigative ophthalmology & visual science · 2025Article
- The stabilized supralinear network accounts for the contrast dependence of visual cortical gamma oscillations.PLoS computational biology · 2024Article
- Decision-related activity and movement selection in primate visual cortex.Science advances · 2024Article
- Visual surround suppression at the neural and perceptual levels.Cognitive neurodynamics · 2024Review
- Multifunctional fibers enable modulation of cortical and deep brain activity during cognitive behavior in macaques.Science advances · 2023Article
- The stabilized supralinear network accounts for the contrast dependence of visual cortical gamma oscillations.bioRxiv : the preprint server for biology · 2023Article
- Transcranial electrical stimulation: How can a simple conductor orchestrate complex brain activity?PLoS biology · 2023Article
- Article
- Neural structure of a sensory decoder for motor control.Nature communications · 2022Article
- What is the dynamical regime of cerebral cortex?Neuron · 2021Review
- Balancing Flexibility and Interference in Working Memory.Annual review of vision science · 2021Review
- Reduced surround suppression in monocular motion perception.Journal of vision · 2021Article
- Inhibitory stabilization and cortical computation.Nature reviews. Neuroscience · 2021Review
- VIP interneurons in mouse primary visual cortex selectively enhance responses to weak but specific stimuli.eLife · 2020Article
- Weaker neural suppression in autism.Nature communications · 2020Article
- Integrated open-source software for multiscale electrophysiology.Scientific data · 2019Article
- Spatial suppression promotes rapid figure-ground segmentation of moving objects.Nature communications · 2019Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
In the visual system, the response to a stimulus in a neuron's receptive field can be modulated by stimulus context, and the strength of these contextual influences vary with stimulus intensity. Recent work has shown how a theoretical model, the stabilized supralinear network (SSN), can account for such modulatory influences, using a small set of computational mechanisms. Although the predictions of the SSN have been confirmed in primary visual cortex (V1), its computational principles apply with equal validity to any cortical structure. We have therefore tested the generality of the SSN by examining modulatory influences in the middle temporal area (MT) of the macaque visual cortex, using electrophysiological recordings and pharmacological manipulations. We developed a novel stimulus that can be adjusted parametrically to be larger or smaller in the space of all possible motion directions. We found, as predicted by the SSN, that MT neurons integrate across motion directions for low-contrast stimuli, but that they exhibit suppression by the same stimuli when they are high in contrast. These results are analogous to those found in visual cortex when stimulus size is varied in the space domain. We further tested the mechanisms of inhibition using pharmacological manipulations of inhibitory efficacy. As predicted by the SSN, local manipulation of inhibitory strength altered firing rates, but did not change the strength of surround suppression. These results are consistent with the idea that the SSN can account for modulatory influences along different stimulus dimensions and in different cortical areas.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.