Evidence map›Paper›PMID 29229700›Full record

ArticleJournal of bacteriology2018

Flexible Hinges in Bacterial Chemoreceptors.

Narahari Akkaladevi, Filiz Bunyak, David Stalla, Tommi A White, Gerald L Hazelbauer

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Structure and signaling mechanism ofbioRxiv : the preprint server for biology · 2026
    Article
  3. Review
  4. A Designed ZnJournal of the American Chemical Society · 2025
    Article
  5. Signal integration in chemoreceptor complexes.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Recent structural advances in bacterial chemotaxis signalling.Current opinion in structural biology · 2023
    Review
  7. Review
  8. Article
  9. Article
  10. Studying bacterial chemosensory array with CryoEM.Biochemical Society transactions · 2021
    Review
  11. Article
  12. Nanodiscs: A toolkit for membrane protein science.Protein science : a publication of the Protein Society · 2021
    Review
  13. Article
  14. Review
  15. Conformational shifts in a chemoreceptor helical hairpin control kinase signaling inProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  16. mBio · 2019
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Narahari AkkaladeviDepartment of Biochemistry, University of Missouri, Columbia, Missouri, USA.
Filiz BunyakDepartment of Computer Science, University of Missouri, Columbia, Missouri, USA.
David StallaElectron Microscopy Core Facility, University of Missouri, Columbia, Missouri, USA.
Tommi A WhiteDepartment of Biochemistry, University of Missouri, Columbia, Missouri, USA.
Gerald L HazelbauerDepartment of Biochemistry, University of Missouri, Columbia, Missouri, USA hazelbauerg@missouri.edu.
University of Missouri · US

Funding

Molecular Studies of Chemoreception: Administrative Supplement for EquipmentR37GM029963 · NIGMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI HAZELBAUER, GERALD L. · 2012 to 2021
$5.7M
MOLECULAR STUDIES OF CHEMORECEPTIONR01GM029963 · NIGMS · WASHINGTON STATE UNIVERSITY · PI HAZELBAUER, GERALD L. · 1985 to 2010
$4.2M
NIGMS NIH HHS R01 GM029963NIGMS NIH HHS R37 GM029963
6 · The paper itself

Abstract

Transmembrane bacterial chemoreceptors are extended, rod-shaped homodimers with ligand-binding sites at one end and interaction sites for signaling complex formation and histidine kinase control at the other. There are atomic-resolution structures of chemoreceptor fragments but not of intact, membrane-inserted receptors. Electron tomography of

Indexed as

Adenylyl CyclasesBacterial Outer Membrane ProteinsBacterial ProteinsBinding SitesEscherichia coliEscherichia coli ProteinsHistidine KinaseImage Processing, Computer-AssistedMethyl-Accepting Chemotaxis ProteinsMicroscopy, Electron, TransmissionModels, MolecularPhosphoric Monoester HydrolasesProtein Array AnalysisReceptors, Amino AcidReceptors, Cell SurfaceSignal TransductionAdenylyl Cyclasesaspartic acid receptorBacterial Outer Membrane ProteinsBacterial ProteinsEscherichia coli ProteinsHistidine KinaseMethyl-Accepting Chemotaxis ProteinsPhosphoric Monoester HydrolasesReceptors, Amino AcidReceptors, Cell SurfaceTar protein, E colibacterial chemotaxishelical coiled coilsprotein arraystransmembrane proteinstransmembrane signaling

Identifiers

PMID29229700
PMCPMC5809691
OpenAlexW2771424982

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.