Evidence map›Paper›PMID 29229699›Full record

ArticleJournal of bacteriology2018

The Nitrogen Regulatory PII Protein (GlnB) and

Irina A Rodionova, Norman Goodacre, Mohan Babu, Andrew Emili, Peter Uetz, Milton H Saier

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Essential Role of LapD in the Absence of Cardiolipins.International journal of molecular sciences · 2026
    Article
  4. Research (Washington, D.C.) · 2026
    Article
  5. Hindguts ofmSystems · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Irina A RodionovaDepartment of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, California, USA irodionova@ucsd.edu msaier@ucsd.edu.
Norman GoodacreCenter for the Study of Biological Complexity, Virginia Commonwealth University, Richmond, Virginia, USA.
Mohan BabuDepartment of Biochemistry, Research and Innovation Centre, University of Regina, Regina, Saskatchewan, Canada.
Andrew EmiliDonnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Peter UetzCenter for the Study of Biological Complexity, Virginia Commonwealth University, Richmond, Virginia, USA.
Milton H SaierDepartment of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, California, USA irodionova@ucsd.edu msaier@ucsd.edu.
University of California, San Diego · USVirginia Commonwealth University · USUniversity of Regina · CAUniversity of Toronto · CA

Funding

The Transporter Classification Database (TCDB)R01GM077402 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SAIER, MILTON H. · 2006 to 2021
$4.7M
Integrative functional mapping of the Escherichia coli membrane interactomeR01GM109895 · NIGMS · VIRGINIA COMMONWEALTH UNIVERSITY · PI SAIER, MILTON H., UETZ, PETER HANS · 2014 to 2017
$1.1M
NIGMS NIH HHS R01 GM077402NIGMS NIH HHS R01 GM109895
6 · The paper itself

Abstract

Amino sugars are good sources of both ammonia and fructose-6-phosphate, produced by the glucosamine 6-phosphate deaminase, NagB. NagB is known to be allosterically regulated by

Indexed as

AcetylglucosamineAldose-Ketose IsomerasesEscherichia coliEscherichia coli ProteinsGene Expression Regulation, BacterialGlucosamineGlucose-6-PhosphateHexosaminesN-Acetylneuraminic AcidNitrogenPhosphorylationPII Nitrogen Regulatory ProteinsProtein Interaction MappingRacemases and EpimerasesSignal TransductionTranscription FactorsAcetylglucosamineAldose-Ketose IsomerasesEscherichia coli ProteinsGlnB protein, E coliGlucosamineglucosamine 6-phosphateglucosamine-6-phosphate isomeraseGlucose-6-PhosphateHexosaminesN-acetylglucosamine 6-phosphateN-acetylmannosamineN-Acetylneuraminic AcidNitrogenPII Nitrogen Regulatory ProteinsRacemases and EpimerasesTranscription Factorsallosteric regulationglucosamine 6-phosphate deaminase/isomeraseN-acetylglucosamine 6-phosphate epimeraseNagBNanEnitrogen regulatorPIIprotein-protein interactionssignal transduction

Identifiers

PMID29229699
PMCPMC5809692
OpenAlexW2773518219

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.