Evidence map›Paper›PMID 29229660›Full record

Observational studyBMJ open2017

Rationale and design of GENEiUS: a prospective observational study on the genetic and environmental determinants of body mass index evolution in Canadian undergraduate students.

Rita E Morassut, Christine Langlois, Akram Alyass, Adeola F Ishola, Fereshteh T Yazdi, Alexandra J Mayhew, Hudson Reddon, James MacKillop, Marie Pigeyre, David Meyre

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Comparing the Trail Users with Trail Non-Users on Physical Activity, Sleep, Mood and Well-Being Index.International journal of environmental research and public health · 2020
    Article
  5. Article
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Rita E MorassutDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada.
Christine LangloisDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada.
Akram AlyassDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada.
Adeola F IsholaDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada.
Fereshteh T YazdiDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada.
Alexandra J MayhewDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada.
Hudson ReddonDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada.
James MacKillopPeter Boris Centre for Addictions Research, McMaster University/St. Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada.
Marie PigeyreDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada.
David MeyreDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada.
Impact · CAMcMaster University · CAUniversité de Lille · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionObesity is a global epidemic and is a risk factor for developing other comorbidities. Young adulthood is a critical period for body weight change and establishing healthy lifestyle behaviours. The 'Freshman 15' suggests that undergraduate students gain 15 lbs (6.8 kg) during their first year of university, although evidence estimates a more modest weight gain of approximately 3-5 lbs (1.4-2.3 kg). Previous studies have only investigated weight change in the first year and do not study potential risk factors. Genetic and EnviroNmental Effects on weight in University Students (GENEiUS) is a prospective observational study which will investigate the environmental and biological determinants of weight change in undergraduate students over 4 years. METHODS AND ANALYSIS: The GENEiUS study will recruit 2500 multiethnic undergraduates aged 17-25 years at McMaster University at the start of their first year and will follow them every 6 months for 4 years. Primary outcomes are obesity traits: body mass index, waist circumference, waist-to-hip ratio, body fat mass and body fat percentage. The contribution of well-established and novel genetic variants for obesity traits and heritability values will be derived from whole-genome single-nucleotide polymorphism genotyping arrays. Civil status, age, sex, ethnicity, length of residence in Canada, religiosity, energy intake, physical activity, exercise motivation, electronic screen time, sleep patterns, history of assault, smoking status, alcohol consumption, medication and drug use, stress, impulsivity, body image perception, self-esteem, anxiety, eating disorders and depression will be investigated for their effect on obesity traits. The findings of the GENEiUS study will be used to help design obesity prevention programme in North American universities with multiethnic populations. ETHICS AND DISSEMINATION: Ethical approval of the study protocol has been obtained from the Hamilton Integrated Research Ethics Board. Study results will be disseminated through scientific publications, scholarly meetings, and collaborative meetings with university administration and student groups.

Indexed as

Body Mass IndexExerciseHealth BehaviorAdiposityAdolescentAdultCanadaFemaleHumansMaleObesityPolymorphism, Single NucleotideProspective StudiesRisk FactorsStudentsUniversitiesenvironmental factorsfreshman 15genetic factorslongitudinalobesityundergraduate students

Identifiers

PMID29229660
PMCPMC5778320
OpenAlexW2772431971

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.