Evidence map›Paper›PMID 29229641›Full record

ArticleAntimicrobial agents and chemotherapy2018

Hyperbaric Oxygen Reduces Aspergillus fumigatus Proliferation

Sourabh Dhingra, Jay C Buckey, Robert A Cramer

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07120581 (Hyperbaric Oxygen Therapy as Salvage Therapy for Healthy, Severely Injured, Mechanically Ventilated Invasive Fungal Infection Cases Resistant to Therapy), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07120581 active not recruitingnot on this mapstarted 2024, after this paper: background citation

Hyperbaric Oxygen Therapy as Salvage Therapy for Healthy, Severely Injured, Mechanically Ventilated Invasive Fungal Infection Cases Resistant to Therapy

Typeobservational_patient_registrySponsorAssaf-Harofeh Medical CenterRan2024 to 2025Enrolled7ConditionsInvasive Fungal Infections, Hyperbaric Oxygen TherapyArmsHyperbaric Oxygen Therapy
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Role of theJournal of fungi (Basel, Switzerland) · 2024
    Article
  7. Review
  8. Review
  9. Review
  10. Novel Insights intoJournal of fungi (Basel, Switzerland) · 2022
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Fungal biofilm architecture produces hypoxic microenvironments that drive antifungal resistance.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  16. Mucormycosis of the Central Nervous System.Journal of fungi (Basel, Switzerland) · 2019
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sourabh DhingraGeisel School of Medicine at Dartmouth, Department of Microbiology and Immunology, Hanover, New Hampshire, USA.
Jay C BuckeyGeisel School of Medicine at Dartmouth, Department of Medicine, Lebanon, New Hampshire, USA.
Robert A CramerGeisel School of Medicine at Dartmouth, Department of Microbiology and Immunology, Hanover, New Hampshire, USA robert.a.cramer.jr@dartmouth.edu.
Dartmouth College · US

Funding

SYNERGY: The Dartmouth Center for clinical and Translational ScienceUL1TR001086 · NCATS · DARTMOUTH COLLEGE · PI GREEN, ALAN I · 2013 to 2017
$18.3M
TRANSLATIONAL RESEARCH COREP30GM106394 · NIGMS · DARTMOUTH COLLEGE · PI STANTON, BRUCE A. · 2013 to 2017
$6.1M
Hypoxia Adaptation and Fungal Virulence of Aspergillus fumigatusR01AI081838 · NIAID · MONTANA STATE UNIVERSITY - BOZEMAN · PI CRAMER, ROBERT ANDREW · 2009 to 2017
$2.9M
NCATS NIH HHS UL1 TR001086NIAID NIH HHS R01 AI081838NIGMS NIH HHS P30 GM106394
6 · The paper itself

Abstract

Recent estimates suggest that more than 3 million people have chronic or invasive fungal infections, causing more than 600,000 deaths every year.

Indexed as

AnimalsAntifungal AgentsAspergillosisAspergillus fumigatusBiofilmsDisease Models, AnimalHyperbaric OxygenationReactive Oxygen SpeciesAntifungal AgentsReactive Oxygen SpeciesAspergillus fumigatusfungal biofilmfungal growthhyperbaric oxygeninvasive aspergillosisoxygen radicals

Identifiers

PMID29229641
PMCPMC5826133
OpenAlexW2791022441

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.