Evidence map›Paper›PMID 29229640›Full record

ArticleAntimicrobial agents and chemotherapy2018

Adverse Effects of Intravenous Vancomycin-Based Prophylaxis during Therapy for Pediatric Acute Myeloid Leukemia.

Yilun Sun, Rachael L Huskey, Li Tang, Hiroto Inaba, Aditya H Gaur, Raul Ribeiro, Jeffrey E Rubnitz, Joshua Wolf

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Observational
  2. Review
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Yilun Sun *Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Rachael L Huskey *Department of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Li TangDepartment of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Hiroto InabaDepartment of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Aditya H GaurDepartment of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Raul RibeiroDepartment of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Jeffrey E RubnitzDepartment of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Joshua WolfDepartment of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee, USA joshua.wolf@stjude.org.
University of Tennessee Health Science Center · USSt. Jude Children's Research Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Children and adolescents with acute myeloid leukemia (AML) are at risk of life-threatening bacterial infections, especially with viridans group streptococci. Primary antibacterial prophylaxis with vancomycin-based regimens reduces this risk but might increase the risks of renal or liver toxicity or

Indexed as

Acute Kidney InjuryAdolescentAnti-Bacterial AgentsChildChild, PreschoolClostridioides difficileClostridium InfectionsFemaleHumansInfantLeukemia, Myeloid, AcuteMaleRetrospective StudiesVancomycinAnti-Bacterial AgentsVancomycinacute kidney injuryantibioticchildClostridium difficileleukemiamyeloidprophylaxisvancomycin

Identifiers

PMID29229640
PMCPMC5826122
OpenAlexW2773348693

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.