ArticlePediatric neurology2018
Dyslipidemia in Children With Arterial Ischemic Stroke: Prevalence and Risk Factors.
Article in Pediatric neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 30 citations in OpenAlex.
- Arterial ischaemic stroke in adolescents and very young adults-results of a European cohort.European stroke journal · 2026Article
- Article
- Comparison of Risk Factors and Outcomes in Pediatric Posterior and Anterior Circulation Arterial Ischemic Stroke: A Cross-Sectional Analysis.Iranian journal of child neurology · 2025Article
- Could headache in children be a biomarker for dyslipidemia?Acta neurologica Belgica · 2024Article
- Risk factors for pediatric ischemic stroke and intracranial hemorrhage: A national electronic health record based study.Heliyon · 2024Article
- Lipoprotein (a): Does It Play a Role in Pediatric Ischemic Stroke and Thrombosis?Current atherosclerosis reports · 2023Review
- Selected Factors of Vascular Changes: The Potential Pathological Processes Underlying Primary Headaches in Children.Children (Basel, Switzerland) · 2022Article
- Serum Levels of Lipids and Selected Aminothiols in Epileptic Children-A Pilot Case-Control Study.Brain sciences · 2022Article
- Hypertriglyceridemia: A Neglected Risk Factor for Ischemic Stroke?Journal of stroke · 2022Review
- Levels of Lipid Parameters in Children with Arterial Ischemic Stroke and Headache: Case-Control Study and Meta-Analysis.Brain sciences · 2021Article
- Headache in Children: Selected Factors of Vascular Changes Involved in Underlying Processes of Idiopathic Headaches.Children (Basel, Switzerland) · 2020Review
- Arterial ischemic stroke in infants, children, and adolescents: results of a Germany-wide surveillance study 2015-2017.Journal of neurology · 2019Article
- Changes in socio-economic status and lipoproteins in Chilean adolescents: a 16-year longitudinal study.Public health nutrition · 2019Article
- Hypertriglyceridemia in Obese Children and Adolescents.Journal of obesity & metabolic syndrome · 2018Review
- Lipoprotein-Associated Phospholipase A2 is Linked with Poor Cardio-Metabolic Profile in Patients with Ischemic Stroke: A Study of Effects of Statins.Journal of neurosciences in rural practiceArticle
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
Abstract
backgroundRisk factors for pediatric stroke are poorly understood and require study to improve prevention. Total cholesterol and triglyceride values peak to near-adult levels before puberty, a period of increased stroke incidence. The role of lipids in childhood arterial ischemic stroke has been minimally investigated.
methodsWe performed a cross-sectional analysis of lipid and Lp(a) concentrations in children with arterial ischemic stroke in the International Pediatric Stroke Study to compare the prevalence of dyslipidemia and high- or low-ranking lipid values in our dataset with reported population values. We analyzed sex, body mass index, race, ethnicity, family history, and stroke risk factors for associations with dyslipidemia, high non-high-density lipoprotein cholesterol, and hypertriglyceridemia.
resultsCompared with the National Health and Nutrition Examination Survey, a higher proportion of children ≥5 years with arterial ischemic stroke had dyslipidemia (38.4% versus 21%), high total cholesterol (10.6% versus 7.4%), high non-high-density lipoprotein cholesterol (23.1% versus 8.4%), and low high-density lipoprotein cholesterol (39.8% versus 13.4%). The lipid values that corresponded to one standard deviation above the mean (84th percentile) in multiple published national studies generally corresponded to a lower ranking percentile in children aged five years or older with arterial ischemic stroke. Dyslipidemia was more likely associated with an underweight, overweight, or obese body mass index compared with a healthy weight. Ethnic background and an acute systemic illness were also associated with abnormal lipids.
conclusionsDyslipidemia and hypertriglyceridemia may be more prevalent in children with arterial ischemic stroke compared with stroke-free children.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.