ReviewJournal of evidence-based complementary & alternative medicine2017
A Mechanistic Review on Medicinal Plants Used for Diabetes Mellitus in Traditional Persian Medicine.
Review in Journal of evidence-based complementary & alternative medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.
- Effect of the Consumption of Species from the Zingiberaceae or Berberidaceae Family on Glycemic Profile Parameters: A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2025Pooled it
- Effects of a hydroalcoholic extract of Juglans regia (walnut) leaves on blood glucose and major cardiovascular risk factors in type 2 diabetic patients: a double-blind, placebo-controlled clinical trial.BMC complementary and alternative medicine · 2018Trial
- Persian Medicinal Plants as Antidiabetic Agents: Mechanisms and Evidence from Bench to Bedside .Iranian biomedical journal · 2025Review
- Plant-Based Diets and Phytochemicals in the Management of Diabetes Mellitus and Prevention of Its Complications: A Review.Nutrients · 2024Review
- Article
- An assessment of the physicochemical characteristics and essential oil composition ofFrontiers in plant science · 2023Article
- Review
- In Vitro Antidiabetic, Antioxidant, and Prebiotic Activities of the Chemical Compounds Isolated fromAntioxidants (Basel, Switzerland) · 2022Article
- Extraction of Bioactive Compounds for Antioxidant, Antimicrobial, and Antidiabetic Applications.Molecules (Basel, Switzerland) · 2022Article
- Nutritional Profiling, Phytochemical Composition and Antidiabetic Potential ofMolecules (Basel, Switzerland) · 2022Article
- Targeting the PI3K/Akt signaling pathway in pancreatic β-cells to enhance their survival and function: An emerging therapeutic strategy for type 1 diabetes.Journal of diabetes · 2022Review
- UHPLC-ESI-QTOF-MSFood science & nutrition · 2022Article
- Metabolites of Prickly Rose: Chemodiversity and Digestive-Enzyme-Inhibiting Potential ofPlants (Basel, Switzerland) · 2021Article
- Antidiabetic effect of fucoxanthin extracted fromFood science & nutrition · 2021Article
- Untargeted Phytochemical Profile, Antioxidant Capacity and Enzyme Inhibitory Activity of Cultivated and Wild Lupin Seeds from Tunisia.Molecules (Basel, Switzerland) · 2021Article
- Middle East Medicinal Plants in the Treatment of Diabetes: A Review.Molecules (Basel, Switzerland) · 2021Review
- Investigation of the Phytochemical Composition, Antioxidant Activity, and Methylglyoxal Trapping Effect ofMolecules (Basel, Switzerland) · 2020Article
- Article
- Phytotherapy in the Management of Diabetes: A Review.Molecules (Basel, Switzerland) · 2018Review
- Anthocyanins in the Management of Metabolic Syndrome: A Pharmacological and Biopharmaceutical Review.Frontiers in pharmacology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes mellitus is the most common endocrine disorder and a major cause of morbidity and mortality. Traditional medicines worldwide suggest a wide range of natural remedies for the prevention and treatment of chronic disorders, including diabetes mellitus. This mechanistic review aims to highlight the significance of medicinal plants traditionally used as dietary supplements in Persian medicine in adjunct with restricted conventional drugs for the prevention and treatment of diabetes mellitus. Mounting evidence suggests that these natural agents perform their protective and therapeutic effect on diabetes mellitus via several cellular mechanisms, including regeneration of pancreatic β cell, limitation of glycogen degradation and gluconeogenesis, anti-inflammatory, immunoregulatory, antiapoptosis, antioxidative stress, as well as modulation of intracellular signaling transduction pathways. In conclusion, traditional medicinal plants used in Persian medicine can be considered as dietary supplements with therapeutic potential for diabetes mellitus and maybe potential sources of new orally active agent(s).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.