Evidence map›Paper›PMID 29228759›Full record

ArticleOncotarget2017

Combination of primary tumor location and mismatch repair status guides adjuvant chemotherapy in stage II colon cancer.

Lin Yang, Wenzhuo He, Qiong Yang, Pengfei Kong, Qiankun Xie, Chang Jiang, Bei Zhang, Liang Ping Xia

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Lin YangSun Yat-Sen University Cancer Center, Guangzhou, China.
Wenzhuo HeSun Yat-Sen University Cancer Center, Guangzhou, China.
Qiong YangSun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Pengfei KongSun Yat-Sen University Cancer Center, Guangzhou, China.
Qiankun XieSun Yat-Sen University Cancer Center, Guangzhou, China.
Chang JiangSun Yat-Sen University Cancer Center, Guangzhou, China.
Bei ZhangSun Yat-Sen University Cancer Center, Guangzhou, China.
Liang Ping XiaSun Yat-Sen University Cancer Center, Guangzhou, China.
Southern Medical University · CNSun Yat-sen University · CNSun Yat-sen University Cancer Center · CNSun Yat-sen Memorial Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrent opinions on the benefits of adjuvant chemotherapy for stage II colon cancer are divided and reformative election of these patients is required. We examined whether the primary tumor location based on mismatch repair status and other risk factors could better inform the current guideline. MATERIALS AND

methodsA total of 673 consecutive patients with stage II colon cancer were included in the analysis. Differences in the common clinicopathological factors between left-sided colon cancer and right-sided colon cancer were analyzed using Fisher's exact analysis. Kaplan-Meier analysis was used to distinguish the survival difference by primary tumor location and/or MMR status.

resultsRCC had a shorter overall survival (

conclusionsThe observed survival benefits in PMMR/RCC patients treated with adjuvant chemotherapy will allow better selection of patients for chemotherapy who are in stage II.

Indexed as

adjuvant chemotherapycolon cancermismatch repairprimary tumor locationsurvival

Identifiers

PMID29228759
PMCPMC5716799
OpenAlexW2766529035

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.