Evidence map›Paper›PMID 29228643›Full record

ReviewOncotarget2017

Estrogen and estrogen receptors in the modulation of gastrointestinal epithelial secretion.

Xin Yang, Yanjun Guo, Jialin He, Fenglian Zhang, Xuemei Sun, Shiming Yang, Hui Dong

Open access · diamondAbstract readReview
In one paragraph

Review in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Hormonal Environment Shapes the Oral Microbiome.Advances in experimental medicine and biology · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. From Menopause to Neurodegeneration-Molecular Basis and Potential Therapy.International journal of molecular sciences · 2021
    Review
  17. Article
  18. Article
  19. Article
  20. Advances in CaExperimental and therapeutic medicine · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Xin YangDepartment of Gastroenterology, Xinqiao Hospital, Third Military Medical University, Chongqing, P.R. China.
Yanjun GuoDepartment of Gastroenterology, Xinqiao Hospital, Third Military Medical University, Chongqing, P.R. China.
Jialin HeDepartment of Gastroenterology, Xinqiao Hospital, Third Military Medical University, Chongqing, P.R. China.
Fenglian ZhangDepartment of Gastroenterology, Xinqiao Hospital, Third Military Medical University, Chongqing, P.R. China.
Xuemei SunDepartment of Gastroenterology, Xinqiao Hospital, Third Military Medical University, Chongqing, P.R. China.
Shiming YangDepartment of Gastroenterology, Xinqiao Hospital, Third Military Medical University, Chongqing, P.R. China.
Hui DongDepartment of Gastroenterology, Xinqiao Hospital, Third Military Medical University, Chongqing, P.R. China.
Army Medical University · CNXinqiao Hospital · CNUniversity of California, San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastrointestinal (GI) epithelial ion transport is physiologically important in many aspects of humans, such as in maintaining fluid balance of whole body, and also plays a role in the development and progression of common GI disease. Estrogen and estrogen receptors have been shown to modulate the activity of epithelial ion secretion in GI tract. This review aims to address the current state of knowledge about the role of estrogen and estrogen receptors in modulation of GI epithelial secretion and to elucidate the underlying mechanisms. We highlight the recent findings regarding the importance of estrogen and estrogen receptors in GI epithelia protection and body fluid balance by modulation of gastrointestinal epithelial HCO

Indexed as

Cl- secretionestrogenestrogen receptorsHCO3- secretion

Identifiers

PMID29228643
PMCPMC5722595
OpenAlexW2618426313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.