Evidence map›Paper›PMID 29228638›Full record

ArticleOncotarget2017

Thoracic radiation-induced pleural effusion and risk factors in patients with lung cancer.

Jing Zhao, Regina M Day, Jian-Yue Jin, Leslie Quint, Hadyn Williams, Catherine Ferguson, Li Yan, Maurice King, Ahmad Albsheer, Martha Matuszak and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  14. Molecular imaging and radionuclide therapy · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jing ZhaoDepartment of Oncology, Tongji Hospital, Tongji Medial College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Regina M DayDepartment of Pharmacology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Jian-Yue JinDepartment of Radiation Oncology, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Leslie QuintDepartment of Radiology, University of Michigan, Ann Arbor, MI, USA.
Hadyn WilliamsDepartment of Radiology, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Catherine FergusonDepartment of Radiation Oncology, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Li YanDepartment of Radiation Oncology, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Maurice KingDepartment of Radiation Oncology, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Ahmad AlbsheerDepartment of Radiation Oncology, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Martha MatuszakDepartment of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
Feng-Ming Spring KongDepartment of Radiation Oncology, Medical College of Georgia, Augusta University, Augusta, GA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The risk factors and potential practice implications of radiation-induced pleural effusion (RIPE) are undefined. This study examined lung cancer patients treated with thoracic radiation therapy (TRT) having follow-up computed tomography (CT) or 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT. Increased volumes of pleural effusion after TRT without evidence of tumor progression was considered RIPE. Parameters of lung dose-volume histogram including percent volumes irradiated with 5-55 Gy (V5-V55) and mean lung dose (MLD) were analyzed by receiver operating characteristic analysis. Clinical and treatment-related risk factors were detected by univariate and multivariate analyses. 175 out of 806 patients receiving TRT with post-treatment imaging were included. 51 patients (24.9%) developed RIPE; 40 had symptomatic RIPE including chest pain (47.1%), cough (23.5%) and dyspnea (35.3%). Female (OR = 0.380, 95% CI: 0.156-0.926,

Indexed as

lung canceroverall survivalradiation induced pleural effusionrisk factorsthoracic radiotherapy

Identifiers

PMID29228638
PMCPMC5722590

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.