Evidence map›Paper›PMID 29228601›Full record

ArticleOncotarget2017

Genome-wide analysis of circular RNAs in prenatal and postnatal muscle of sheep.

Cunyuan Li, Xiaoyue Li, Yang Yao, Qiman Ma, Wei Ni, Xiangyu Zhang, Yang Cao, Wureli Hazi, Dawei Wang, Renzhe Quan and 7 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 40 citations in OpenAlex.

  1. CircularRNA and Musculoskeletal Diseases.Advances in experimental medicine and biology · 2025
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. The Roles of CircRNAs in Regulating Muscle Development of Livestock Animals.Frontiers in cell and developmental biology · 2021
    Review
  14. Article
  15. Article
  16. Review
  17. Circular RNAs in myogenesis.Biochimica et biophysica acta. Gene regulatory mechanisms · 2020
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Cunyuan LiCollege of Life Sciences, Shihezi University, Shihezi, Xinjiang, 832003, China.
Xiaoyue LiCollege of Life Sciences, Shihezi University, Shihezi, Xinjiang, 832003, China.
Yang YaoCollege of Life Sciences, Shihezi University, Shihezi, Xinjiang, 832003, China.
Qiman MaCollege of Life Sciences, Shihezi University, Shihezi, Xinjiang, 832003, China.
Wei NiCollege of Life Sciences, Shihezi University, Shihezi, Xinjiang, 832003, China.
Xiangyu ZhangCollege of Life Sciences, Shihezi University, Shihezi, Xinjiang, 832003, China.
Yang CaoCollege of Life Sciences, Shihezi University, Shihezi, Xinjiang, 832003, China.
Wureli HaziCollege of Animal Science and Technology, Shihezi University, Shihezi, Xinjiang, 832003, China.
Dawei WangCollege of Life Sciences, Shihezi University, Shihezi, Xinjiang, 832003, China.
Renzhe QuanCollege of Life Sciences, Shihezi University, Shihezi, Xinjiang, 832003, China.
Xiaoxu HouCollege of Life Sciences, Shihezi University, Shihezi, Xinjiang, 832003, China.
Zhijin LiuCollege of Life Sciences, Shihezi University, Shihezi, Xinjiang, 832003, China.
Qianqian ZhanCollege of Life Sciences, Shihezi University, Shihezi, Xinjiang, 832003, China.
Li LiuCollege of Life Sciences, Shihezi University, Shihezi, Xinjiang, 832003, China.
Mengdan ZhangCollege of Life Sciences, Shihezi University, Shihezi, Xinjiang, 832003, China.
Shuting YuCollege of Life Sciences, Shihezi University, Shihezi, Xinjiang, 832003, China.
Shengwei HuCollege of Life Sciences, Shihezi University, Shihezi, Xinjiang, 832003, China.
Shihezi University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circular RNAs (circRNAs), a type of non-coding RNA with circular structure, were generated by back splicing and widely expressed in animals and plants. Recent studies have shown that circRNAs extensively participate in cell proliferation, cell differentiation, cell autophagy and other biological processes. However, the role and expression of circRNAs in the development and growth of muscle have not been studied in sheep. In our study, we first used RNA-seq to study the circRNAs in prenatal and postnatal longissimus dorsi muscle of sheep. A total of 6113 circRNAs were detected from the RNA-seq data. Several circRNAs were identified using reverse transcription PCR, DNA sequencing and RNase R digestion experiments. The expression levels of several circRNAs in prenatal and postnatal muscle were confirmed by Real-Time RT-PCR. The gene ontology (GO) and KEGG enrichment analysis of the host gene of the circRNAs showed that these circRNAs were mainly involved in the growth and development of muscle related signaling pathways. These circRNAs might sponge microRNAs (miRNAs) in predicted circRNA-miRNA-mRNA networks. The circRNAs expression profiles in muscle provided an important reference for the study of circRNAs in sheep.

Indexed as

circRNAsexpression profilesmuscleRNA-seqsheep

Identifiers

PMID29228601
PMCPMC5722553
OpenAlexW2767085919

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.