Evidence map›Paper›PMID 29228574›Full record

ArticleOncotarget2017

Microfluidic hydrodynamic focusing synthesis of polymer-lipid nanoparticles for siRNA delivery.

Xueqin Huang, Robert J Lee, Yuhang Qi, Yujing Li, Jiahui Lu, Qingfan Meng, Lesheng Teng, Jing Xie

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
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  8. Review
  9. Therapeutic Effect and Mechanisms of the Novel Monosulfactam 0073.Antimicrobial agents and chemotherapy · 2020
    Article
  10. Review
  11. Microfluidic tools for lipid production and modification: a review.Environmental science and pollution research international · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Xueqin HuangSchool of Life Sciences, Jilin University, Changchun, Jilin 130023, China.
Robert J LeeSchool of Life Sciences, Jilin University, Changchun, Jilin 130023, China.
Yuhang QiSchool of Life Sciences, Jilin University, Changchun, Jilin 130023, China.
Yujing LiSchool of Life Sciences, Jilin University, Changchun, Jilin 130023, China.
Jiahui LuSchool of Life Sciences, Jilin University, Changchun, Jilin 130023, China.
Qingfan MengSchool of Life Sciences, Jilin University, Changchun, Jilin 130023, China.
Lesheng TengSchool of Life Sciences, Jilin University, Changchun, Jilin 130023, China.
Jing XieSchool of Life Sciences, Jilin University, Changchun, Jilin 130023, China.
Jilin University · CNThe Ohio State University · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Jennifer A. Woyach · 1985 to 2026
$132.3M
NCI NIH HHS P30 CA016058
6 · The paper itself

Abstract

Small interfering RNAs (siRNAs) are promising as therapeutics for intractable diseases such as cancer. However, efficient and safe delivery of siRNAs

Indexed as

cancer treatmentlipid nanoparticlesmicrofluidicpolymersiRNA delivery

Identifiers

PMID29228574
PMCPMC5722526
OpenAlexW2619051200

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.