Evidence map›Paper›PMID 29228566›Full record

ArticleOncotarget2017

Targeting CXCR4 with [

Constantin Lapa, Stefan Kircher, Andreas Schirbel, Andreas Rosenwald, Saskia Kropf, Theo Pelzer, Thorsten Walles, Andreas K Buck, Wolfgang A Weber, Hans-Juergen Wester and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Imaging of pleural disease.Breathe (Sheffield, England) · 2024
    Review
  6. CXCR4-targeted theranostics in oncology.European journal of nuclear medicine and molecular imaging · 2022
    Review
  7. Current Status ofDiagnostics (Basel, Switzerland) · 2022
    Review
  8. Review
  9. Article
  10. CXCR4-Directed Imaging in Solid Tumors.Frontiers in oncology · 2019
    Article
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Constantin LapaDepartment of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
Stefan KircherInstitute of Pathology, University of Würzburg, Comprehensive Cancer Center Mainfranken (CCCMF), Würzburg, Germany.
Andreas SchirbelDepartment of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
Andreas RosenwaldInstitute of Pathology, University of Würzburg, Comprehensive Cancer Center Mainfranken (CCCMF), Würzburg, Germany.
Saskia KropfScintomics GmbH, Fürstenfeldbruck, Germany.
Theo PelzerDepartment of Internal Medicine I, Division of Pulmonology, Universitätsklinikum Würzburg, Würzburg, Germany.
Thorsten WallesDepartment of Thoracic Surgery, University Hospital Magdeburg, Magdeburg, Germany.
Andreas K BuckDepartment of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
Wolfgang A WeberMolecular Imaging and Therapy Service, Memorial Sloan-Kettering Cancer Center and Weill-Cornell Medical College, New York, New York, USA.
Hans-Juergen WesterPharmaceutical Radiochemistry, Technische Universität München, Munich, Germany.
Ken HerrmannDepartment of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
Katharina LückerathDepartment of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
Universitätsklinikum Würzburg · DEUniversity of Würzburg · DEMemorial Sloan Kettering Cancer Center · USTechnical University of Munich · DEUniversity Hospital Magdeburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

C-X-C motif chemokine receptor 4 (CXCR4) is a key factor for tumor growth and metastasis in several types of human cancer. This study investigated the feasibility of CXCR4-directed imaging with positron emission tomography/computed tomography (PET/CT) using [

Indexed as

[68Ga] pentixaforCXCR4PETpleural mesotheliomatheranostics

Identifiers

PMID29228566
PMCPMC5722518
OpenAlexW2618094660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.