Evidence map›Paper›PMID 29228149›Full record

ArticleEuropean heart journal2018

Outcome after transvascular transcatheter aortic valve implantation in 2016.

Luise Gaede, Johannes Blumenstein, Christoph Liebetrau, Oliver Dörr, Won-Keun Kim, Holger Nef, Oliver Husser, Albrecht Elsässer, Christian W Hamm, Helge Möllmann

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in European heart journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 72 citations in OpenAlex.

  1. Cost-effectiveness of population screening for aortic stenosis.European heart journal. Quality of care & clinical outcomes · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Transcatheter-based aortic valve replacement vs. isolated surgical aortic valve replacement in 2020.Clinical research in cardiology : official journal of the German Cardiac Society · 2022
    Article
  8. Review
  9. Article
  10. Aortic valve replacement in Germany in 2019.Clinical research in cardiology : official journal of the German Cardiac Society · 2021
    Article
  11. Kidney injury as post-interventional complication of TAVI.Clinical research in cardiology : official journal of the German Cardiac Society · 2021
    Review
  12. Article
  13. European heart health survey 2019.Clinical cardiology · 2020
    Article
  14. Transcatheter aortic valve implantation in nonagenarians: insights from the German Aortic Valve Registry (GARY).Clinical research in cardiology : official journal of the German Cardiac Society · 2020
    Article
  15. Pacemaker implantation after aortic valve replacement: rapid-deployment Intuity® compared to conventional bioprostheses.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2020
    Article
  16. Lower mortality in an all-comers aortic stenosis population treated with TAVI in comparison to SAVR.Clinical research in cardiology : official journal of the German Cardiac Society · 2020
    Article
  17. Transvascular transcatheter aortic valve implantation in 2017.Clinical research in cardiology : official journal of the German Cardiac Society · 2020
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Luise GaedeDepartment of Internal Medicine, St.-Johannes-Hospital, Johannesstraße 9-13, 44137 Dortmund, Germany.
Johannes BlumensteinDepartment of Internal Medicine, St.-Johannes-Hospital, Johannesstraße 9-13, 44137 Dortmund, Germany.
Christoph LiebetrauDepartment of Cardiology, Kerckhoff Heart and Thorax Center, Benekestraße 2-8, 61231 Bad Nauheim, Germany.
Oliver DörrMedical Clinic I, Department of Cardiology and Angiology, University of Giessen, Klinikstraße 33, 35392 Giessen, Germany.
Won-Keun KimDepartment of Cardiology, Kerckhoff Heart and Thorax Center, Benekestraße 2-8, 61231 Bad Nauheim, Germany.
Holger NefMedical Clinic I, Department of Cardiology and Angiology, University of Giessen, Klinikstraße 33, 35392 Giessen, Germany.
Oliver HusserDepartment of Internal Medicine, St.-Johannes-Hospital, Johannesstraße 9-13, 44137 Dortmund, Germany.
Albrecht ElsässerDepartment of Cardiology, Klinikum Oldenburg, Rahel-Straus-Straße 10, 26133 Oldenburg, Germany.
Christian W HammDepartment of Cardiology, Kerckhoff Heart and Thorax Center, Benekestraße 2-8, 61231 Bad Nauheim, Germany.
Helge MöllmannDepartment of Internal Medicine, St.-Johannes-Hospital, Johannesstraße 9-13, 44137 Dortmund, Germany.
St.-Johannes-Hospital Dortmund · DEKerckhoff Klinik · DEUniversity of Giessen · DEKlinikum Oldenburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: We analysed the number of procedures, complications, and in-hospital mortality rates of all patients undergoing transvascular transcatheter aortic valve implantation (TV-TAVI) in comparison to isolated surgical aortic valve replacement (iSAVR) from 2014 to 2016 in Germany. Methods and results: All aortic valve procedures performed in Germany are mandatorily registered in a quality control program. More than 15 000 TV-TAVI procedures were performed in 2016 in Germany. Especially the number of post-procedural complications declined within the last few years, including new pacemaker implantations (2015: 12.6% vs. 2016: 11.4%, P = 0.002) and vascular complications (2015: 8.5% vs. 2016: 7.1%; P < 0.001). Thus, in 2016 the overall in-hospital mortality rate after TV-TAVI was 2.6%, which is for the first time numerically below that of iSAVR, which was 2.9% (P = 0.19). A stratified analysis according to the German aortic valve score shows a lower observed than expected in-hospital mortality rate for TV-TAVI (O/E 0.68). Additionally, the in-hospital mortality was significantly lower after TV-TAVI than after iSAVR in the very high- (11.3% vs. 23.6%; P < 0.001), in the high- (4.1% vs. 9.2%; P < 0.001), and in the intermediate-risk group (3.0% vs. 4.6%; P = 0.016) and was similar to that of iSAVR in low-risk patients (1.6% vs. 1.4%; P = 0.4). Conclusion: The overall in-hospital mortality after TV-TAVI was numerically lower than after iSAVR in 2016 for the first time. In the low risk group in-hospital mortality was similar, whereas in all other risk groups in-hospital mortality after TV-TAVI was significantly lower than after SAVR. This is likely to contribute to a redefinition of the standard of care in the future.

Indexed as

AgedAged, 80 and overAge FactorsAortic Valve StenosisFemaleGermanyHeart Valve Prosthesis ImplantationHospital MortalityHumansMaleMiddle AgedPostoperative ComplicationsSurvival AnalysisTranscatheter Aortic Valve ReplacementTreatment Outcome

Identifiers

PMID29228149
PMCPMC5837346
OpenAlexW2771511619

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.