Evidence map›Paper›PMID 29227860›Full record

ArticleJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2018

Respiratory syncytial virus in Brazilian infants - Ten years, two cohorts.

Elinara Wollmeister, Alfonso Eduardo Alvarez, Juliana Cristina Santiago Bastos, Fernando Augusto Lima Marson, José Dirceu Ribeiro, Emílio Carlos Elias Baracat, Clarice Weis Arns, Adriana Gut Lopes Riccetto

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Elinara WollmeisterDepartment of Pediatrics, Faculty of Medical Sciences, University of Campinas - Unicamp, São Paulo, Brazil. Electronic address: elinaraw@gmail.com.
Alfonso Eduardo AlvarezDepartment of Pediatrics, Faculty of Medical Sciences, University of Campinas - Unicamp, São Paulo, Brazil; Center for Research in Pediatrics (CIPED), Department of Pediatrics, Faculty of Medical Sciences, University of Campinas - Unicamp, São Paulo, Brazil. Electronic address: alfonso@imunevida.com.br.
Juliana Cristina Santiago BastosDepartment of Genetics, Evolution and Bioagents, Biology Institute, University of Campinas - Unicamp, São Paulo, Brazil. Electronic address: jusantiago_farmacia@yahoo.com.br.
Fernando Augusto Lima MarsonDepartment of Pediatrics, Faculty of Medical Sciences, University of Campinas - Unicamp, São Paulo, Brazil; Center for Research in Pediatrics (CIPED), Department of Pediatrics, Faculty of Medical Sciences, University of Campinas - Unicamp, São Paulo, Brazil; Department of Medical Genetics, Faculty of Medical Sciences, University of Campinas - Unicamp, São Paulo, Brazil. Electronic address: fernandolimamarson@hotmail.com.
José Dirceu RibeiroDepartment of Pediatrics, Faculty of Medical Sciences, University of Campinas - Unicamp, São Paulo, Brazil; Center for Research in Pediatrics (CIPED), Department of Pediatrics, Faculty of Medical Sciences, University of Campinas - Unicamp, São Paulo, Brazil. Electronic address: jdirceuribeiro@gmail.com.
Emílio Carlos Elias BaracatDepartment of Pediatrics, Faculty of Medical Sciences, University of Campinas - Unicamp, São Paulo, Brazil. Electronic address: ebaracat@fcm.unicamp.br.
Clarice Weis ArnsDepartment of Genetics, Evolution and Bioagents, Biology Institute, University of Campinas - Unicamp, São Paulo, Brazil. Electronic address: arns@unicamp.br.
Adriana Gut Lopes RiccettoDepartment of Pediatrics, Faculty of Medical Sciences, University of Campinas - Unicamp, São Paulo, Brazil. Electronic address: aglriccetto@gmail.com.
Universidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEach year, a considerable amount of children will experience at least one episode of acute viral bronchiolitis (AVB) during their first year of life. About 10% of them will be hospitalized, with significant physical and economic burdens.

objectivesTo compare two cohorts of infants with AVB, from same region, in a ten-year interval, regarding epidemiologic factors and viral etiology. STUDY

designCohorts: 142 (2004) and 172 (2014) infants at ages zero to 12 months; clinical diagnosis of AVB; medical care in hospital and genetic screening of nasopharyngeal secretion for respiratory viruses.

resultsThe comparative analysis showed a difference in the percentage of respiratory syncytial virus (RSV) positive patients [2004 (33.1%); 2014 (70.3%)] (p<0.01). No differences were noted regarding gender, breastfeeding, tobacco exposure, crowding and maternal education. There was a difference as to the month of incidence (seasonality) of AVB (higher in April 2014). There was a higher age at attendance in the first cohort, and lower birth weight and gestational age ratios in the second cohort (p<0.05). There were no differences in hospitalization time, need of mechanical ventilation and number of deaths, however a difference regarding co-morbidities was noted (higher in 2004) (p<0.001).

conclusionNone of the analyzed variables had an impact on severity features. Virology and immunology must be considered in this kind of situation, by studying genetic variants and the maturation of the immune system in AVB by RSV or other viruses.

Indexed as

BrazilBronchiolitisCohort StudiesFemaleHospitalizationHumansIncidenceInfantInfant, NewbornMaleNasopharynxRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsAcute viral bronchiolitisClinical dataEpidemiologic dataPolymerase chain reactionRespiratory syncytial virusRespiratory viruses

Identifiers

PMID29227860
PMCPMC7106499
OpenAlexW2774753281

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.