Evidence map›Paper›PMID 29226878›Full record

ArticleAsian journal of andrology

ASIC1a contributes to the symptom of pain in a rat model of chronic prostatitis.

Song Fan, Zong-Yao Hao, Li Zhang, Jun Zhou, Yi-Fei Zhang, Shen Tai, Xian-Sheng Zhang, Chao-Zhao Liang

Open access · goldAbstract read
In one paragraph

Article in Asian journal of andrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Signaling Pathways in Proton and Non-proton ASIC1a Activation.Frontiers in cellular neuroscience · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Song FanDepartment of Urology, Institute of Urology, Anhui Medical University, Hefei 230022, China.
Zong-Yao HaoDepartment of Urology, Institute of Urology, Anhui Medical University, Hefei 230022, China.
Li ZhangDepartment of Urology, Institute of Urology, Anhui Medical University, Hefei 230022, China.
Jun ZhouDepartment of Urology, Institute of Urology, Anhui Medical University, Hefei 230022, China.
Yi-Fei ZhangDepartment of Urology, Institute of Urology, Anhui Medical University, Hefei 230022, China.
Shen TaiDepartment of Urology, Institute of Urology, Anhui Medical University, Hefei 230022, China.
Xian-Sheng ZhangDepartment of Urology, Institute of Urology, Anhui Medical University, Hefei 230022, China.
Chao-Zhao LiangDepartment of Urology, Institute of Urology, Anhui Medical University, Hefei 230022, China.
First Affiliated Hospital of Anhui Medical University · CNAnhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to validate our hypothesis that acid-sensing ion channels (ASICs) may contribute to the symptom of pain in patients with chronic prostatitis (CP). We first established a CP rat model, then isolated the L5-S2 spinal dorsal horn neurons for further studies. ASIC1a was knocked down and its effects on the expression of neurogenic inflammation-related factors in the dorsal horn neurons of rat spinal cord were evaluated. The effect of ASIC1a on the Ca

Indexed as

Acid Sensing Ion Channel BlockersAcid Sensing Ion ChannelsAnimalsCalciumChelating AgentsChronic DiseaseCytokinesDisease Models, AnimalEgtazic AcidGene Knockdown TechniquesImidazolesInflammationMaleMAP Kinase Signaling Systemp38 Mitogen-Activated Protein KinasesPain1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl esterAcid Sensing Ion Channel BlockersAcid Sensing Ion ChannelsAsic1 protein, ratCalciumChelating AgentsCytokinesEgtazic AcidImidazolesp38 Mitogen-Activated Protein KinasesPcTX1 protein, Psalmopoeus cambridgeiPeptidesProtein Kinase InhibitorsPyridinesSB 203580Spider VenomsASIC1achronic prostatitispain symptom

Identifiers

PMID29226878
PMCPMC5952487
OpenAlexW2801646860

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.