Evidence map›Paper›PMID 29226706›Full record

ReviewAIDS research and human retroviruses2018

Natural Products and HIV/AIDS.

Daniele C Cary, B Matija Peterlin

Abstract readReview
In one paragraph

Review in AIDS research and human retroviruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Molecules (Basel, Switzerland) · 2022
    Article
  11. Review
  12. Review
  13. Bioactive Compounds fromPharmaceuticals (Basel, Switzerland) · 2021
    Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Daniele C Cary1 Department of Medicine, University of California at San Francisco , San Francisco, California.
B Matija Peterlin1 Department of Medicine, University of California at San Francisco , San Francisco, California.

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
TAT TransactivationR01AI125104 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PETERLIN, BORIS MATIJA · 2016 to 2020
$2.0M
NIAID NIH HHS P30 AI027763NIAID NIH HHS R01 AI125104
6 · The paper itself

Abstract

The study of natural products in biomedical research is not a modern concept. Many of the most successful medical therapeutics are derived from natural products, including those studied in the field of HIV/AIDS. Biomedical research has a rich history of discovery based on screens of medicinal herbs and traditional medicine practices. Compounds derived from natural products, which repress HIV and those that activate latent HIV, have been reported. It is important to remember the tradition in medical research to derive therapies based on these natural products and to overcome the negative perception of natural products as an "alternative medicine."

Indexed as

Anti-HIV AgentsBiological ProductsHIV-1HIV InfectionsHumansPlants, MedicinalVirus LatencyVirus ReplicationAnti-HIV AgentsBiological ProductsAIDSHIVHIV reactivationHIV suppressionnatural products

Identifiers

PMID29226706
PMCPMC5771529

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.