Evidence map›Paper›PMID 29226633›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2018

Characterization of Membrane Patch-Ion Channel Probes for Scanning Ion Conductance Microscopy.

Wenqing Shi, Yuhan Zeng, Cheng Zhu, Yucheng Xiao, Theodore R Cummins, Jianghui Hou, Lane A Baker

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Scanning Ion Conductance Microscopy.Chemical reviews · 2021
    Review
  4. Article
  5. Imaging with Ion Channels.Analytical chemistry · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wenqing ShiDepartment of Chemistry, Indiana University, 800 E. Kirkwood Avenue, Bloomington, IN, 47405, USA.
Yuhan ZengDepartment of Chemistry, Indiana University, 800 E. Kirkwood Avenue, Bloomington, IN, 47405, USA.
Cheng ZhuDepartment of Chemistry, Indiana University, 800 E. Kirkwood Avenue, Bloomington, IN, 47405, USA.
Yucheng XiaoDepartment of Biology, Stark Neurosciences Research Institute, Indiana University-Purdue University Indianapolis, 723 West Michigan Street, SL-306, Indianapolis, IN, 46202, USA.
Theodore R CumminsDepartment of Biology, Stark Neurosciences Research Institute, Indiana University-Purdue University Indianapolis, 723 West Michigan Street, SL-306, Indianapolis, IN, 46202, USA.
Jianghui HouDepartment of Internal Medicine - Renal Division, Division of Biological and Biochemical Sciences, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8126, St. Louis, MO, 63110, USA.
Lane A BakerDepartment of Chemistry, Indiana University, 800 E. Kirkwood Avenue, Bloomington, IN, 47405, USA.ORCID 0000-0001-5127-507X

Funding

Bio/Chemical Mapping of Pancreatic Cell ActivityR21EB022297 · NIBIB · TRUSTEES OF INDIANA UNIVERSITY · PI BAKER, LANE A. · 2016 to 2017
$407k
NIBIB NIH HHS R21 EB022297
6 · The paper itself

Abstract

Integration of dual-barrel membrane patch-ion channel probes (MP-ICPs) to scanning ion conductance microscopy (SICM) holds promise of providing a revolutionized approach of spatially resolved chemical sensing. A series of experiments are performed to further the understanding of the system and to answer some fundamental questions, in preparation for future developments of this approach. First, MP-ICPs are constructed that contain different types of ion channels including transient receptor potential vanilloid 1 and large conductance Ca2

Indexed as

Ion ChannelsIon TransportMicroscopyPorosityIon Channelsbiosensorsion channelsscanned probes

Identifiers

PMID29226633
PMCPMC6955111

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.