Evidence map›Paper›PMID 29226507›Full record

ArticleAmerican journal of hematology2018

Age is a predictor of a small decrease in lung function in children with sickle cell anemia.

Shaina M Willen, Robyn Cohen, Mark Rodeghier, Fenella Kirkham, Susan S Redline, Carol Rosen, Jane Kirkby, Michael R DeBaun

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in American journal of hematology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Respiratory management of acute chest syndrome in children with sickle cell disease.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  10. The Cardiopulmonary Complications of Sickle Cell Disease.Hematology/oncology clinics of North America · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Shaina M WillenDepartment of Pediatrics, Division of Hematology/Oncology, Vanderbilt-Meharry Center for Excellence in Sickle Cell Disease, Vanderbilt University Medical Center, Nashville, Tennessee.ORCID 0000-0002-6691-816X
Robyn CohenDepartment of Pediatrics, Division of Pediatric Pulmonary and Allergy, Boston University School of Medicine, Boston, Massachusetts.
Mark RodeghierRodeghier Consultants, Chicago, Illinois.
Fenella KirkhamDevelopmental Neurosciences Unit, UCL Great Ormond Street, Institute of Child Health, London, United Kingdom.
Susan S RedlineDepartment of Medicine and Neurology, Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, Massachusetts.
Carol RosenDepartment of Pediatrics, Division of Pediatric Pulmonary, Allergy/Immunology and Sleep, University Hospitals-Cleveland Medical Center, Rainbow Babies and Children's Hospitals, Cleveland, Ohio.
Jane KirkbyRespiratory, Critical Care and Anaesthesia, UCL Great Ormond Street, Institute of Child Health, University College London, London, United Kingdom.
Michael R DeBaunDepartment of Pediatrics, Division of Hematology/Oncology, Vanderbilt-Meharry Center for Excellence in Sickle Cell Disease, Vanderbilt University Medical Center, Nashville, Tennessee.ORCID 0000-0002-0574-1604
Vanderbilt University Medical Center · USBoston University · USBrigham and Women's Hospital · USGreat Ormond Street Hospital · GBRainbow Babies & Children's Hospital · USUniversity College London · GB

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024989 · NCRR · CASE WESTERN RESERVE UNIVERSITY · PI DAVIS, PAMELA B · 2007 to 2011
$53.7M
Asthma and Nocturnal Hypoxemia in Sickle Cell Anemia IIR01HL079937 · NHLBI · WASHINGTON UNIVERSITY · PI DEBAUN, MICHAEL R., STRUNK, ROBERT · 2005 to 2013
$10.4M
Clinical and Translational Training Program in Pulmonary MedicineT32HL087738 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Lorraine B Ware · 2007 to 2026
$7.0M
NCRR NIH HHS UL1 RR024989NHLBI NIH HHS R01 HL079937NHLBI NIH HHS T32 HL087738
6 · The paper itself

Abstract

The longitudinal pattern of lung function in children with sickle cell anemia (SCA) has shown a decrease in FEV

Indexed as

Age FactorsForced Expiratory VolumeAcute Chest SyndromeAdolescentAnemia, Sickle CellAsthmabeta-ThalassemiaChildChild, PreschoolDisease ProgressionFemaleFollow-Up StudiesHumansHydroxyureaLungLung Volume MeasurementsHydroxyurea

Identifiers

PMID29226507
PMCPMC5803370
OpenAlexW2771108259

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.