Evidence map›Paper›PMID 29226300›Full record

Trial reportProgress in orthodontics2017

A novel method for treatment of Class III malocclusion in growing patients.

Saad A Al-Mozany, Oyku Dalci, Mohammed Almuzian, Carmen Gonzalez, Nour E Tarraf, M Ali Darendeliler

Open access · diamondAbstract readClinical Trial
In one paragraph

Trial report in Progress in orthodontics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 58 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Retrospective Descriptive Case Series on the Use of AMCOPBioengineering (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Article
  7. Skeletal Anchorage in Class III Malocclusion in Early Adolescence.International journal of clinical pediatric dentistry · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Comparison of the short-term effects of facemask therapy preceded by conventional rapid maxillary expansion or by an alternate rapid maxillary expansions and constrictions protocol : A retrospective study.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Maxillary protraction in patients with unilateral cleft lip and palate : Evaluation of soft and hard tissues using the Alt-RAMEC protocol.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2020
    Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Saad A Al-MozanyDiscipline of Orthodontics, Faculty of Dentistry, University of Sydney, Sydney, Australia.
Oyku DalciDiscipline of Orthodontics, Faculty of Dentistry, University of Sydney, Sydney, Australia.
Mohammed AlmuzianDiscipline of Orthodontics, Faculty of Dentistry, University of Sydney, Sydney, Australia. dr_muzian@hotmail.com.
Carmen GonzalezDiscipline of Orthodontics, Faculty of Dentistry, University of Sydney, Sydney, Australia.
Nour E TarrafDiscipline of Orthodontics, Faculty of Dentistry, University of Sydney, Sydney, Australia.
M Ali DarendelilerDiscipline of Orthodontics, Faculty of Dentistry, University of Sydney, Sydney, Australia.
University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundManagement of Class III malocclusion is one of the most challenging treatments in orthodontics, and several methods have been advocated for treatment of this condition. A new treatment protocol involves the use of an alternating rapid maxillary expansion and constriction (Alt-RAMEC) protocol, in conjunction with full-time Class III elastic wear and coupled with the use of temporary anchorage devices (TADs). The aim of this study was to evaluate the dento-skeletal and profile soft tissue effects of this novel protocol in growing participants with retrognathic maxilla.

methodsFourteen growing participants (7 males and 7 females; 12.05 ± 1.09 years), who displayed Class III malocclusions with retrognathic maxilla, were recruited. Pre-treatment records were taken before commencing treatment (T1). All participants had a hybrid mini-implant-supported rapid maxillary expansion (MARME) appliance that was activated by the Alt-RAMEC protocol for 9 weeks. Full-time bone-anchored Class III elastics, delivering 400 g/side, were then used for maxillary protraction. When positive overjet was achieved, protraction was ceased and post-treatment records were taken (T2). Linear and angular cephalometric variables were blindly measured by one investigator and repeated after 1 month. An error measurement (Dahlberg's formula) study was performed to evaluate the intra-examiner reliability. A paired-sample t test (p < 0.05) was used to compare each variable from T1 to T2.

resultsTreatment objectives were achieved in all participants within 8.5 weeks of protraction. The maxilla significantly protracted (SNA 1.87°± 1.06°; Vert.T-A 3.29± 1.54 mm p < 0.001), while the mandibular base significantly redirected posteriorly (SNB -2.03° ± 0.85°, Vert.T-B - 3.43± 4.47 mm, p < 0.001 and p < 0.05 respectively), resulting in a significant improvement in the jaw relationship (ANB 3.95°± 0.57°, p < 0.001; Wits 5.15± 1.51 mm, p < 0.001). The Y-axis angle increased significantly (1.95° ± 1.11°, p < 0.001). The upper incisors were significantly proclined (+ 2.98°± 2.71°, p < 0.01), coupled with a significant retroclination of the lower incisors (- 3.2°± 3.4°, p < 0.05). The combined skeletal and dental effects significantly improved the overjet (5.62± 1.36 mm, p < 0.001) and the soft tissue Harmony angle (2.75° ± 1.8°, p < 0.001).

conclusionsClass III elastics, combined with the Alt-RAMEC activation protocol of the MARPE appliance, is an efficient treatment method for mild/moderate Class III malocclusions. The long-term stability of these changes needs further evaluation.

Indexed as

Child DevelopmentCephalometryChildClinical ProtocolsFemaleHumansMaleMalocclusion, Angle Class IIIOrthodontic Anchorage ProceduresOrthodontic Appliance DesignPalatal Expansion TechniqueTreatment OutcomeVertical Dimension

Identifiers

PMID29226300
PMCPMC5723582
OpenAlexW2766819278

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.