ArticleScience advances2017
Tip-enhanced ablation and ionization mass spectrometry for nanoscale chemical analysis.
Article in Science advances, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 45 citations in OpenAlex.
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- Microlensed fiber allows subcellular imaging by laser-based mass spectrometry.Nature protocols · 2023Review
- Adatom Bonding Sites in a Nickel-FeAngewandte Chemie (International ed. in English) · 2022Article
- Direct analysis of surface chemicals using vibrating sharp-edge spray ionization mass spectrometry.Rapid communications in mass spectrometry : RCM · 2020Article
- Nanoscale laser-induced breakdown spectroscopy imaging reveals chemical distribution with subcellular resolution.Nanoscale advances · 2020Article
- Present and Future of Surface-Enhanced Raman Scattering.ACS nano · 2020Article
- Exploiting the native inspiratory ability of a mass spectrometer to improve analysis efficiency.RSC advances · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spectroscopic methods with nanoscale lateral resolution are becoming essential in the fields of physics, chemistry, geology, biology, and materials science. However, the lateral resolution of laser-based mass spectrometry imaging (MSI) techniques has so far been limited to the microscale. This report presents the development of tip-enhanced ablation and ionization time-of-flight mass spectrometry (TEAI-TOFMS), using a shell-isolated apertureless silver tip. The TEAI-TOFMS results indicate the capability and reproducibility of the system for generating nanosized craters and for acquiring the corresponding mass spectral signals. Multi-elemental analysis of nine inorganic salt residues and MSI of a potassium salt residue pattern at a 50-nm lateral resolution were achieved. These results demonstrate the opportunity for the distribution of chemical compositions at the nanoscale to be visualized.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.