Evidence map›Paper›PMID 29226191›Full record

ArticleGlobal pediatric health2017

Time to Drug-Resistant Tuberculosis Treatment in a Prospective South African Cohort.

Brittney J van de Water, Janet Prvu Bettger, Susan Silva, Janice Humphreys, Coleen K Cunningham, Jason E Farley

Open access · goldAbstract read
In one paragraph

Article in Global pediatric health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
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  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Brittney J van de WaterHarvard Medical School, Boston, MA, USA.
Janet Prvu BettgerDuke University, Durham, NC, USA.
Susan SilvaDuke University, Durham, NC, USA.
Janice HumphreysDuke University, Durham, NC, USA.
Coleen K CunninghamDuke University, Durham, NC, USA.
Jason E FarleyJohns Hopkins University, Baltimore, MD, USA.
Duke University · USHarvard University · USJohns Hopkins University · US

Funding

Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI Nwora Lance Okeke · 2005 to 2026
$50.5M
A Nurse Case Management Intervention to Improve MDR-TB/HIV Coinfection OutcomesR01AI104488 · NIAID · JOHNS HOPKINS UNIVERSITY · PI FARLEY, JASON EDWARD · 2014 to 2019
$3.2M
NIAID NIH HHS P30 AI064518NIAID NIH HHS R01 AI104488
6 · The paper itself

Abstract

This study examined time to treatment initiation by age among a prospective cohort with drug-resistant tuberculosis (DR-TB). Participants aged 13 years or older nested within a cluster-randomized trial in 2 South African provinces were evaluated. Outcomes were treatment initiation within 5 days of DR-TB diagnosis (National Tuberculosis Program guidelines) and days from diagnosis to treatment. A total of 521 participants met inclusion criteria. Eighty-two patients (16%) met national guidelines; median time to treatment was 11 days (range = 0-180). No patient (age, sex, prior TB history, HIV status) or health system characteristics (geographic urban/rural location, province) were associated with treatment initiation per guidelines except geographic location (

Indexed as

adolescent medicinedrug-resistanceinfectious diseasestreatmenttuberculosis

Identifiers

PMID29226191
PMCPMC5714082
OpenAlexW2773001187

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.