Evidence map›Paper›PMID 29226156›Full record

ReviewJournal of immunology research2017

MicroRNAs Regulate Thymic Epithelium in Age-Related Thymic Involution via Down- or Upregulation of Transcription Factors.

Minwen Xu, Xiaoli Zhang, Ruiyun Hong, Dong-Ming Su, Liefeng Wang

Open access · goldAbstract readReview
In one paragraph

Review in Journal of immunology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Regulatory RNAs in immunosenescence.Immunity, inflammation and disease · 2024
    Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Minwen XuFirst Affiliated Hospital, Gannan Medical University, Ganzhou 341000, China.ORCID 0000-0001-7754-7387
Xiaoli ZhangDepartment of Biotechnology, Gannan Medical University, Ganzhou 341000, China.ORCID 0000-0002-7686-6965
Ruiyun HongFirst Affiliated Hospital, Gannan Medical University, Ganzhou 341000, China.ORCID 0000-0002-8367-7337
Dong-Ming SuInstitute for Molecular Medicine, University of North Texas Health Science Center, Fort Worth, TX 76107, USA.ORCID 0000-0002-3326-4753
Liefeng WangDepartment of Biotechnology, Gannan Medical University, Ganzhou 341000, China.ORCID 0000-0003-4787-4533
First Affiliated Hospital of Gannan Medical University · CNUniversity of North Texas · USGannan Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-related thymic involution is primarily induced by defects in nonhematopoietic thymic epithelial cells (TECs). It is characterized by dysfunction of multiple transcription factors (TFs), such as

Indexed as

3' Untranslated RegionsAgingAnimalsEpitheliumGene Expression RegulationHumansMicroRNAsRegenerationThymus GlandTranscription Factors3' Untranslated RegionsMicroRNAsTranscription Factors

Identifiers

PMID29226156
PMCPMC5684555
OpenAlexW2753786952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.