ArticleCurrent tropical medicine reports2016
Human Brucellosis and Adverse Pregnancy Outcomes.
Article in Current tropical medicine reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Follow-up outcomes of asymptomatic brucellosis: a systematic review and meta-analysis.Emerging microbes & infections · 2023Pooled it
- Building the Evidence Base for the Prevention of Raw Milk-Acquired Brucellosis: A Systematic Review.Frontiers in public health · 2020Pooled it
- A systematic review and meta-analysis of the prevalence of osteoarticular brucellosis.PLoS neglected tropical diseases · 2019Pooled it
- Development of in-house PCR assays and cross-sectional molecular surveillance of infectious pathogens in adverse pregnancy outcomes and neonatal sepsis in central India.BMC infectious diseases · 2026Article
- Glucose uptake is essential forInfection and immunity · 2025Article
- Brucellosis in pregnancy: a case report.AME case reports · 2025Article
- Article
- Brucellosis in cattle and buffalo in southern Italian provinces: trends in presence of territory-specific One Health measures.Frontiers in microbiology · 2025Article
- Article
- An 8000 years old genome reveals the Neolithic origin of the zoonosis Brucella melitensis.Nature communications · 2024Article
- Septicemia caused bySAGE open medical case reports · 2024Article
- Maternal, Fetal, and Neonatal Outcomes of Gestation in Women with and WithoutJournal of research in health sciences · 2023Article
- Activation of mucosal immunity as a novel therapeutic strategy for combating brucellosis.Frontiers in microbiology · 2022Review
- Prevalence and relevant factors of positive RF in brucellosis patients with arthralgia.PLoS neglected tropical diseases · 2021Article
- Article
- Human brucellosis in pregnancy - an overview.Bosnian journal of basic medical sciences · 2020Review
- Brucella abortus and Pregnancy in Mice: Impact of Chronic Infection on Fertility and the Role of Regulatory T Cells in Tissue Colonization.Infection and immunity · 2020Article
- Helping to heal nature and ourselves through human-rights-based and gender-responsive One Health.One health outlook · 2020Review
- Vaccine safety studies ofVaccine: X · 2019Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
purpose of reviewBrucellosis is a neglected, zoonotic disease of nearly worldwide distribution. Despite brucellosis being recognized as a reproductive disease in animals, it has been historically known as a flu-like illness in humans with little or no significant role in maternal or newborn health. This review focuses on what is currently known relative to the epidemiology of brucellosis in human pregnancy as well as new insights of placental immunology. RECENT
findingsNew evidence suggests that maternal infection poses a significant risk factor for adverse pregnancy outcomes including increased risk for miscarriage during the first and second trimester of gestation, preterm delivery, and vertical transmission to the fetus. Adverse pregnancy outcomes were not associated with any specific clinical sign. However, prompt diagnosis and treatment significantly decreased the risk of miscarriage or any other adverse effect. SUMMARY: Brucellosis during pregnancy should be considered a significant risk factor for adverse pregnancy outcomes in humans. The identification of the mechanism behind bacterial tropism should prove powerful for the development of new countermeasures to prevent these detrimental effects. Increased awareness concerning brucellosis in pregnant women, its transmission, and prevention measures should be considered as a pressing need.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.