ArticleRehabilitation research and practice2017
Modulation of H-Reflex Depression with Paired-Pulse Stimulation in Healthy Active Humans.
Article in Rehabilitation research and practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Musculoskeletal Plasticity After Spinal Cord Injury
Long Duration Activity and Metabolic Control After Spinal Cord Injury
Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- The Hoffmann Reflex.NeuroSci · 2026Review
- Optimizing Hoffmann Reflex Rate-Dependent Depression: A Feasible Protocol for Assessing Spinal Inhibition in Upper and Lower Limbs.Medical sciences (Basel, Switzerland) · 2026Article
- A pilot study of spinal reflex modulation during immersive virtual reality exposure in humans.Frontiers in human neuroscience · 2026Article
- Optimizing assessment of low frequency H-reflex depression in persons with spinal cord injury.PloS one · 2024Article
- Lack of Evidence for Crossover Fatigue with Plantar Flexor Muscles.Journal of sports science & medicine · 2022Article
- Myotonic dystrophy type 1 alters muscle twitch properties, spinal reflexes, and perturbation-induced trans-cortical reflexes.Muscle & nerve · 2020Article
- Hybrid stimulation enhances torque as a function of muscle fusion in human paralyzed and non-paralyzed skeletal muscle.The journal of spinal cord medicine · 2019Article
- Sustained submaximal contraction yields biphasic modulation of soleus Post-activation depression in healthy humans.Scandinavian journal of medicine & science in sports · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Depression of the Hoffman reflex (H-reflex) is used to examine spinal control mechanisms during exercise, fatigue, and vibration and in response to training. H-reflex depression protocols frequently use trains of stimuli; this is time-consuming and prevents instantaneous assessment of motor neuronal excitability. The purpose of this study was to determine if paired-pulse H-reflex depression is reproducible and whether paired-pulse stimulation adequately estimates the depression induced by the more traditional ten-pulse train. H-reflexes were elicited via ten-pulse trains at 0.1, 0.2, 1, 2, and 5 Hz in ten neurologically intact individuals on two separate days. We measured the depression elicited by the second pulse (H2) and the mean depression elicited by pulses 2-10 (Hmean). H2 was consistent at all frequencies on both days (
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.