ArticleRMD open2017
Relationship between shift work and the onset of rheumatoid arthritis.
Article in RMD open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 35 citations in OpenAlex.
- Unhealthy sleep patterns and irregular night shift work are associated with increased risk of allergic rhinitis: a large prospective cohort study.BMC public health · 2026Article
- The association between the American heart association's new "Life's Essential 8" and different types of arthritis: insights from a large population study.Scientific reports · 2025Observational
- Circadian Rhythm Disruption Exacerbates Autoimmune Uveitis: The Essential Role of PER1 in Treg Cell Metabolic Support for Stability and Function.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Sleep patterns, physical activity, genetic susceptibility, and incident rheumatoid arthritis: a prospective cohort study.BMC medicine · 2024Article
- The Associations of Chronotype and Shift Work With Rheumatoid Arthritis.Journal of biological rhythms · 2023Article
- Causality of occupational exposure on rheumatoid arthritis and ankylosing spondylitis: a two-sample mendelian randomization study.Frontiers in immunology · 2023Article
- Adaptive immunity, chronic inflammation and the clock.Seminars in immunopathology · 2022Review
- Identifying hub circadian rhythm biomarkers and immune cell infiltration in rheumatoid arthritis.Frontiers in immunology · 2022Article
- Metabolic Profiling of Serum for Osteoarthritis Biomarkers.Disease markers · 2022Article
- Chrono-moxibustion adjusts circadian rhythm of CLOCK and BMAL1 in adjuvant-induced arthritic rats.American journal of translational research · 2022Article
- Exposure to silica and systemic sclerosis: A retrospective cohort study based on the Canadian Scleroderma Research Group.Frontiers in medicine · 2022Article
- IgG subclass and Fc glycosylation shifts are linked to the transition from pre- to inflammatory autoimmune conditions.Frontiers in immunology · 2022Review
- Potential effects of shift work on skin autoimmune diseases.Frontiers in immunology · 2022Review
- The Association Between the Number of Consecutive Night Shifts and Insomnia Among Shift Workers: A Multi-Center Study.Frontiers in public health · 2021Article
- Night work, mortality, and the link to occupational group and sex.Scandinavian journal of work, environment & health · 2020Article
- Melatonin Is a Feasible, Safe, and Acceptable Intervention in Doctors and Nurses Working Nightshifts: The MIDNIGHT Trial.Frontiers in psychiatry · 2020Article
- Moxibustion benignantly regulates circadian rhythm of REV-ERBα in RA rats.American journal of translational research · 2020Review
- Psoriatic and psoriatic arthritis patients with and without jet-lag: does it matter for disease severity scores? Insights and implications from a pilot, prospective study.Chronobiology international · 2019Article
- Shift work and cognitive impairment in later life - results of a cross-sectional pilot study testing the feasibility of a large-scale epidemiologic investigation.BMC public health · 2018Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEnvironmental factors play a prominent role in rheumatoid arthritis (RA) aetiology
methodsThe present report is based on a population-based, case-control study with incident cases of RA (1951 cases and 2225 controls matched by age, gender and residential area). Using logistic regression, occurrence of RA among subjects who have been exposed to different kinds of shift work was compared with that among those who have never been exposed by calculating the OR with a 95% CI.
resultsRotating shift work and day-oriented shift work increased the risk of developing ACPA-positive RA (OR 1.3, 95% CI 1.0 to 1.7 and OR 1.3, 95% CI 1.0 to 1.6), but not ACPA-negative RA. Permanent night shift work appeared to be a protective factor both against ACPA-positive RA (OR 0.7, 95% CI 0.6 to 0.9) and ACPA-negative RA (OR 0.8, 95% CI 0.6 to 1.0). For both subsets of RA, significant trends showed a lower risk of developing RA with increasing duration of permanent night shift work (p value for trend 0.002 vs 0.04).
conclusionsSleep restriction as a consequence of shift work is associated with several biological effects among which changes in melatonin production may be involved. The present epidemiological findings of a complex relationship between sleep patterns and different forms of RA may be of importance for increasing the understanding of the pathophysiology of RA.
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