ArticleClinical kidney journal2017
Renal denervation using carbon dioxide renal angiography in patients with uncontrolled hypertension and moderate to severe chronic kidney disease.
Article in Clinical kidney journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Pooled it
- Effects of renal denervation on kidney function in patients with chronic kidney disease: a systematic review and meta-analysis.Journal of human hypertension · 2024Pooled it
- Efficacy and safety of a modified ozone-mediated neurolysis in treatment for patients with resistant hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Trial
- Carbon Dioxide Angiography-Guided Ultrasound Renal Denervation in Refractory Hypertension With Chronic Kidney Disease.JACC. Case reports · 2026Article
- Safety and Efficacy of Renal Denervation for the Treatment of Resistant Hypertension in Patients with Chronic Kidney Disease: A Narrative Review of the Literature.Biomedicines · 2025Review
- Effects of renal denervation on the kidney: albuminuria, proteinuria, and renal function.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Review
- New Aspects in the Management of Hypertension in Patients with Chronic Kidney Disease not on Renal Replacement Therapy.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2022Review
- Renal artery intervention utilizing carbon dioxide angiography.Clinical kidney journal · 2017Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic kidney disease (CKD) is the most common cause of secondary hypertension. More than half of the patients have uncontrolled hypertension (≥140/90 mmHg on three or more antihypertensive agents at optimum doses). Renal sympathetic denervation (RSDN) has been shown to reduce blood pressure (BP) in patients with resistant hypertension. Although patients with CKD have high sympathetic drive, all major clinical trials have excluded patients with estimated glomerular filtration rates (eGFRs) <45 mL/min/1.73m
methodsIn this pilot study, carbon dioxide (CO
resultsEleven patients (eight males) underwent RSDN. The median age was 57 years [interquartile range (IQR) 49-66]. The median number of antihypertensives being taken at baseline was 4 (IQR 3-4). No statistically significant difference was observed in serum creatinine in the serial follow-ups until at 6 months[median difference 0.25 mg/dL (IQR 0.09-0.53); P = 0.008]. There was a non-significant reduction in median clinic BP from baseline to 6 months [-14 mmHg (IQR -24-5)] and a significant increase in daytime ambulatory systolic BP [7 mmHg (IQR -2-12); P= 0.045]. A trend towards a serial reduction in albuminuria was observed. Procedure-related complications included a groin haematoma (
conclusionsThis pilot study shows that CO
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.