Evidence map›Paper›PMID 29225797›Full record

ArticleAntimicrobial resistance and infection control2017

Seasonal clustering of sinopulmonary mucormycosis in patients with hematologic malignancies at a large comprehensive cancer center.

Shobini Sivagnanam, Dhruba J Sengupta, Daniel Hoogestraat, Rupali Jain, Zach Stednick, David N Fredricks, Paul Hendrie, Estella Whimbey, Sara T Podczervinski, Elizabeth M Krantz and 2 more

Open access · goldAbstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Rhino-Orbito-Cerebral Mucormycosis During the Second Wave of Covid-19: The Indian Scenario.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  4. Prognostication of Sino-Nasal Mucormycosis.Iranian journal of otorhinolaryngology · 2022
    Article
  5. COVID-19 and Fungal Diseases.Antibiotics (Basel, Switzerland) · 2022
    Review
  6. Article
  7. COVID-19-associated mucormycosis of head-and-neck region: A systematic review.Journal of clinical and translational research · 2022
    Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Isavuconazole Prophylaxis in Patients With Hematologic Malignancies and Hematopoietic Cell Transplant Recipients.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  15. Review
  16. How Clean Is the Linen at My Hospital? The Mucorales on Unclean Linen Discovery Study of Large United States Transplant and Cancer Centers.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Shobini SivagnanamVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. North, E4-100, Seattle, WA 98109 USA.ORCID 0000-0003-1028-7087
Dhruba J SenguptaDepartment of Laboratory Medicine, University of Washington Medical Center, Seattle, WA USA.
Daniel HoogestraatDepartment of Laboratory Medicine, University of Washington Medical Center, Seattle, WA USA.
Rupali JainDepartment of Pharmacy, University of Washington Medical Center, Seattle, WA USA.
Zach StednickVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. North, E4-100, Seattle, WA 98109 USA.
David N FredricksVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. North, E4-100, Seattle, WA 98109 USA.
Paul HendrieClincial Research Division, Fred Hutchinson Cancer Res. Ctr, Seattle, WA USA.
Estella WhimbeyDepartment of Medicine, University of Washington Medical Center, Seattle, WA USA.
Sara T PodczervinskiWashington State Department of Health, Shoreline, WA USA.
Elizabeth M KrantzVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. North, E4-100, Seattle, WA 98109 USA.
Jeffrey S DuchinPublic Health, Seattle and King County, Seattle, WA USA.
Steven A PergamVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. North, E4-100, Seattle, WA 98109 USA.
University of Washington Medical Center · USCape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa · ZAFred Hutch Cancer Center · USPublic Health – Seattle & King County · USWashington State Department of Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Invasive Mucorales infections (IMI) lead to significant morbidity and mortality in immunocompromised hosts. The role of season and climatic conditions in case clustering of IMI remain poorly understood. Methods: Following detection of a cluster of sinopulmonary IMIs in patients with hematologic malignancies, we reviewed center-based medical records of all patients with IMIs and other invasive fungal infections (IFIs) between January of 2012 and August of 2015 to assess for case clustering in relation to seasonality. Results: A cluster of 7 patients were identified with sinopulmonary IMIs ( Conclusions: Sinopulmonary Mucorales clusters at our center had a seasonal variation which appeared to be related to temperature and precipitation. Given the significant mortality associated with IMIs, local climatic conditions may need to be considered when considering center specific fungal prevention and prophylaxis strategies for high-risk patients.

Indexed as

Academic Medical CentersCross InfectionSeasonsAdultAgedDisease OutbreaksFemaleGeography, MedicalHematologic NeoplasmsHumansMaleMiddle AgedMucormycosisRespiratory MucosaClimateFungusHealthcare-associated infectionsImmunocompromised hostMoldMucormycosisSeasonal

Identifiers

PMID29225797
PMCPMC5718160
OpenAlexW2771732327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.