Evidence map›Paper›PMID 29225671›Full record

ReviewChild and adolescent psychiatry and mental health2017

Tourette syndrome and other neurodevelopmental disorders: a comprehensive review.

Elena Cravedi, Emmanuelle Deniau, Marianna Giannitelli, Jean Xavier, Andreas Hartmann, David Cohen

Abstract readReview
In one paragraph

Review in Child and adolescent psychiatry and mental health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Tourette syndrome.Nature reviews. Disease primers · 2026
    Review
  6. Article
  7. Observational
  8. Article
  9. Review
  10. Co-design of the neurodevelopment assessment scale.Frontiers in child and adolescent psychiatry · 2025
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elena CravediDepartment of Child and Adolescent Psychiatry, Pitié-Salpêtrière Hospital, APHP, 83, boulevard de l'hôpital, 75013 Paris, France.ORCID 0000-0002-4906-3200
Emmanuelle DeniauDepartment of Child and Adolescent Psychiatry, Pitié-Salpêtrière Hospital, APHP, 83, boulevard de l'hôpital, 75013 Paris, France.
Marianna GiannitelliDepartment of Child and Adolescent Psychiatry, Pitié-Salpêtrière Hospital, APHP, 83, boulevard de l'hôpital, 75013 Paris, France.
Jean XavierDepartment of Child and Adolescent Psychiatry, Pitié-Salpêtrière Hospital, APHP, 83, boulevard de l'hôpital, 75013 Paris, France.
Andreas HartmannDepartment of Neurology, Reference Centre for Tourette Syndrome, Pitié-Salpêtrière Hospital, APHP, Paris, France.
David CohenDepartment of Child and Adolescent Psychiatry, Pitié-Salpêtrière Hospital, APHP, 83, boulevard de l'hôpital, 75013 Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gilles de la Tourette syndrome (TS) is a complex developmental neuropsychiatric condition in which motor manifestations are often accompanied by comorbid conditions that impact the patient's quality of life. In the DSM-5, TS belongs to the "neurodevelopmental disorders" group, together with other neurodevelopmental conditions, frequently co-occurring. In this study, we searched the PubMed database using a combination of keywords associating TS and all neurodevelopmental diagnoses. From 1009 original reports, we identified 36 studies addressing TS and neurodevelopmental comorbidities. The available evidence suggests the following: (1) neurodevelopmental comorbidities in TS are the rule, rather than the exception; (2) attention deficit/hyperactivity disorder (ADHD) is the most frequent; (3) there is a continuum from a simple (TS + ADHD or/and learning disorder) to a more complex phenotype (TS + autism spectrum disorder). We conclude that a prompt diagnosis and a detailed description of TS comorbidities are necessary not only to understand the aetiological basis of neurodevelopmental disorders but also to address specific rehabilitative and therapeutic approaches.

Indexed as

ADHDAutismNeurodevelopmental disorderTourette

Identifiers

PMID29225671
PMCPMC5715991

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.