Evidence map›Paper›PMID 29225664›Full record

ArticleJournal of simulation : JOS2017

Load balancing for multi-threaded PDES of stochastic reaction-diffusion in neurons.

Zhongwei Lin, Carl Tropper, Yiping Yao, Robert A Mcdougal, Mohammand Nazrul Ishlam Patoary, William W Lytton, Michael L Hines

Open access · greenAbstract read
In one paragraph

Article in Journal of simulation : JOS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Zhongwei LinState Key Laboratory of High Performance Computing, National University of Defense Technology, China.
Carl TropperSchool of Computer Science, McGill University, Canada.
Yiping YaoCollege of Information System and Management, National University of Defense Technology, China.
Robert A McdougalDepartment of Neurobiology, Yale University, USA.
Mohammand Nazrul Ishlam PatoarySchool of Computer Science, McGill University, Canada.
William W LyttonSUNY Downstate Medical Center, USA.
Michael L HinesDepartment of Neurobiology, Yale University, USA.
McGill University · CANational University of Defense Technology · CNYale University · USSUNY Downstate Health Sciences University · US

Funding

MEDICAL INFORMATICS RESEARCH TRAINING AT YALET15LM007056 · NLM · YALE UNIVERSITY · PI Mark Bender Gerstein, LUCILA OHNO-MACHADO · 1987 to 2026
$22.2M
Extension of NEURON simulator for simulation of reaction-diffusion in neuronsR01MH086638 · NIMH · SUNY DOWNSTATE MEDICAL CENTER · PI LYTTON, WILLIAM W, MCDOUGAL, ROBERT A. · 2010 to 2025
$6.0M
NIMH NIH HHS R01 MH086638NLM NIH HHS T15 LM007056
6 · The paper itself

Abstract

Stochastic simulation of chemical reactions and diffusion in a neuron helps to provide a realistic view of the molecular dynamics within a neuron. We developed a multi-threaded PDES simulator, Neuron Time Warp-Multi Thread, suitable for the stochastic simulation of reaction and diffusion in a neuron. In this paper we make use of Q-Learning and Simulated Annealing to determine the parameters for a dynamic load balancing algorithm and for dynamic window control. During the simulation, the runtime statistics of each thread are collected and used to determine the execution time of the simulation. Based upon this assessment, workload is migrated from the most overloaded threads to the most under-load ones. As the results for a calcium wave model show, both approaches can improve the execution time for small simulations by up to 31% (Q-Learning) and 19% (SA). The simulated annealing approach is more suitable for larger populations, decreasing execution time by 41%.

Indexed as

Load BalancingMulti-threaded PDESQ-LearningSimulated AnnealingStochastic Neuronal SimulationWindow Control

Identifiers

PMID29225664
PMCPMC5720372
OpenAlexW2533263508

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.