ReviewIranian endodontic journal2017
Genotoxicity, Bioactivity and Clinical Properties of Calcium Silicate Based Sealers: A Literature Review.
Review in Iranian endodontic journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Endodontic sealers based on calcium silicates: a systematic review.Odontology · 2019Pooled it
- Comparative Finite Element Analysis of Stress Concentration in Class V Lower Premolar Cavities Differently Restored by Adhesive Dental Materials.European journal of dentistry · 2026Article
- Cytotoxicity and genotoxicity evaluation of AH Plus, Well-Root ST, and AH Plus Bioceramic Sealer.BMC oral health · 2025Article
- A Novel Niosomal Doxycycline/Triamcinolone Medicament Matches Calcium Hydroxide for Low Tooth Staining: A 4-WeekIranian endodontic journal · 2025Article
- Modern methods and materials used to treat root perforation: effectiveness comparison.Journal of materials science. Materials in medicine · 2024Article
- Genotoxicity and Cytotoxicity Comparison of Calcium Silicate-Based and Resin-Based Sealers on Human Periodontal Ligament Stem Cells.European endodontic journal · 2022Article
- Article
- Periodontal response to a tricalcium silicate material or resin composite placed in close contact to the supracrestal tissue attachment: a histomorphometric comparative study.Clinical oral investigations · 2021Article
- Could the Calcium Silicate-Based Sealer Presentation Form Influence Dentinal Sealing? An In Vitro Confocal Laser Study on Tubular Penetration.Materials (Basel, Switzerland) · 2021Article
- Different Application Methods for Endoseal MTA Sealer: A Comparative Study.Iranian endodontic journal · 2020Article
- Bacterial Percolation and Sealer Tubular Penetration in a Polymer-based Obturation System Compared with Warm Vertical Condensation Technique: AnIranian endodontic journal · 2020Article
- Evaluation of Selective Physicochemical and Biological Properties of Different Root Canal Sealers.Iranian endodontic journal · 2019Article
- Physical Properties, Cytocompatibility and Sealability of HealApex (a Novel Premixed Biosealer).Iranian endodontic journal · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An ideal endodontic sealer should have many properties such as excellent seal after setting, dimensional stability, slow setting time to ensure sufficient working time, insolubility to tissue fluids, adequate adhesion with canal walls and biocompatibility. Genotoxicity is one of the important factors that influence biocompatibility of an endodontic sealer. This literature review was conducted to survey the genotoxicity, bioactivity and clinical perspectives of calcium silicate based sealers. We searched PubMed using appropriate MeSH keywords. Also a hand search was conducted in the related journals. Sixty eight articles were assessed finally. Genotoxicity and acute inflammation were high in calcium silicate based sealers. Both resin-based and calcium silicate based sealers caused perceptible tooth discoloration. There were controversies regarding the fracture resistance, apical patency and retreatability of different sealers. Clinical properties of calcium silicate-based sealers are also outlined.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.