Evidence map›Paper›PMID 29225627›Full record

ArticleStem cells international2017

Isolation and Molecular Characterization of Amniotic Fluid-Derived Mesenchymal Stem Cells Obtained from Caesarean Sections.

Lucas-Sebastian Spitzhorn, Md Shaifur Rahman, Laura Schwindt, Huyen-Tran Ho, Wasco Wruck, Martina Bohndorf, Silke Wehrmeyer, Audrey Ncube, Ines Beyer, Carsten Hagenbeck and 3 more

Abstract read
In one paragraph

Article in Stem cells international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Lucas-Sebastian Spitzhorn *Institute for Stem Cell Research and Regenerative Medicine, Heinrich Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.ORCID 0000-0002-2335-6881
Md Shaifur Rahman *Institute for Stem Cell Research and Regenerative Medicine, Heinrich Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.
Laura SchwindtInstitute for Stem Cell Research and Regenerative Medicine, Heinrich Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.
Huyen-Tran HoInstitute for Stem Cell Research and Regenerative Medicine, Heinrich Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.
Wasco WruckInstitute for Stem Cell Research and Regenerative Medicine, Heinrich Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.
Martina BohndorfInstitute for Stem Cell Research and Regenerative Medicine, Heinrich Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.
Silke WehrmeyerInstitute for Stem Cell Research and Regenerative Medicine, Heinrich Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.
Audrey NcubeInstitute for Stem Cell Research and Regenerative Medicine, Heinrich Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.
Ines BeyerDepartment of Obstetrics and Gynaecology, Heinrich Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.ORCID 0000-0001-7468-4466
Carsten HagenbeckDepartment of Obstetrics and Gynaecology, Heinrich Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.
Percy BalanDepartment of Obstetrics and Gynaecology, Heinrich Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.
Tanja FehmDepartment of Obstetrics and Gynaecology, Heinrich Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.
James AdjayeInstitute for Stem Cell Research and Regenerative Medicine, Heinrich Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.ORCID 0000-0002-6075-6761

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human amniotic fluid cells are immune-privileged with low immunogenicity and anti-inflammatory properties. They are able to self-renew, are highly proliferative, and have a broad differentiation potential, making them amenable for cell-based therapies. Amniotic fluid (AF) is routinely obtained via amniocentesis and contains heterogeneous populations of foetal-derived progenitor cells including mesenchymal stem cells (MSCs). In this study, we isolated human MSCs from AF (AF-MSCs) obtained during Caesarean sections (C-sections) and characterized them. These AF-MSCs showed typical MSC characteristics such as morphology,

Identifiers

PMID29225627
PMCPMC5684599

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.