Evidence map›Paper›PMID 29225574›Full record

ArticleFrontiers in human neuroscience2017

Motor Unit Activity during Fatiguing Isometric Muscle Contraction in Hemispheric Stroke Survivors.

Lara McManus, Xiaogang Hu, William Z Rymer, Nina L Suresh, Madeleine M Lowery

Open access · goldAbstract read
In one paragraph

Article in Frontiers in human neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  8. Imbalanced Subthreshold Currents Following Sepsis and Chemotherapy: A Shared Mechanism Offering a New Therapeutic Target?The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Lara McManusNeuromuscular Systems Lab, School of Electrical and Electronic Engineering, University College Dublin, Belfield, Ireland.
Xiaogang HuJoint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill, NC, United States.
William Z RymerShirley Ryan AbilityLab, Chicago, IL, United States.
Nina L SureshShirley Ryan AbilityLab, Chicago, IL, United States.
Madeleine M LoweryNeuromuscular Systems Lab, School of Electrical and Electronic Engineering, University College Dublin, Belfield, Ireland.
University College Dublin · IENorthwestern University · USShirley Ryan AbilityLab · USUniversity of North Carolina at Chapel Hill · US

Funding

Origins of Increased Motoneuron Excitability in Hemispheric StrokeR01HD089952 · NICHD · REHABILITATION INSTITUTE OF CHICAGO D/B/A SHIRLEY RYAN ABILITYLAB · PI RYMER, WILLIAM ZEV · 2016 to 2020
$1.6M
NICHD NIH HHS R01 HD089952
6 · The paper itself

Abstract

Enhanced muscle weakness is commonly experienced following stroke and may be accompanied by increased susceptibility to fatigue. To examine the contributions of central and peripheral factors to isometric muscle fatigue in stroke survivors, this study investigates changes in motor unit (MU) mean firing rate, and action potential duration during, and directly following, a sustained submaximal fatiguing contraction at 30% maximum voluntary contraction (MVC). A series of short contractions of the first dorsal interosseous muscle were performed pre- and post-fatigue at 20% MVC, and again following a 10-min recovery period, by 12 chronic stroke survivors. Individual MU firing times were extracted using surface EMG decomposition and used to obtain the spike-triggered average MU action potential waveforms. During the sustained fatiguing contraction, the mean rate of change in firing rate across all detected MUs was greater on the affected side (-0.02 ± 0.03 Hz/s) than on the less-affected side (-0.004 ± 0.003 Hz/s,

Indexed as

isometric fatiguemotor unitmotor unit action potentialmotor unit firing ratestrokesurface EMG decomposition

Identifiers

PMID29225574
PMCPMC5705653
OpenAlexW2769996240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.