ArticleJournal of atherosclerosis and thrombosis2018
Omentin-1 is Associated with Carotid Plaque Instability among Ischemic Stroke Patients.
Article in Journal of atherosclerosis and thrombosis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 36 citations in OpenAlex.
- Omentin-General Overview of Its Role in Obesity, Metabolic Syndrome and Other Diseases; Problem of Current Research State.Biomedicines · 2025Review
- CircSKA3 is Associated With the Risk of Extracranial Artery Stenosis and Plaque Instability Among Ischemic Stroke Patients.Cellular and molecular neurobiology · 2024Article
- Article
- Association of Serum Omentin-1 Concentration with the Content of Adipose Tissue and Glucose Tolerance in Subjects with Central Obesity.Biomedicines · 2023Article
- The Role of Anti-Inflammatory Adipokines in Cardiometabolic Disorders: Moving beyond Adiponectin.International journal of molecular sciences · 2021Review
- Omentin Is Independently Associated with Stroke Severity and Ipsilateral Carotid Artery Stenosis in Patients with Acute Cerebral Ischemia.Journal of clinical medicine · 2021Article
- Expression of adipokines in children with primary nephrotic syndrome and its association with hyperlipidemia.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021Article
- Serum omentin-1 levels in hypertensive patients.Journal of human hypertension · 2021Article
- Non-stenotic Carotid Plaques in Embolic Stroke of Unknown Source.Frontiers in neurology · 2021Review
- Search for Reliable Circulating Biomarkers to Predict Carotid Plaque Vulnerability.International journal of molecular sciences · 2020Review
- Clinical relevance of serum omentin-1 levels as a biomarker of prognosis in patients with acute cerebral infarction.Brain and behavior · 2020Article
- Increased Release of Proinflammatory Proteins in Primary Human Adipocytes and Activation of the Inflammatory NFĸB, p38, and ERK Pathways upon Omentin Treatment.Obesity facts · 2020Article
- [Application of Logistic regression and decision tree analysis in prediction of acute myocardial infarction events].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2019Article
- Plasma omentin levels are inversely associated with atherosclerosis in type 2 diabetes patients with increased plasma adiponectin levels: a cross-sectional study.Cardiovascular diabetology · 2019Article
- Blood Biomarkers for Stroke Diagnosis and Management.Neuromolecular medicine · 2019Review
- Time-Dependent Change in Omentin-1 Level Correlated with Early Improvement of Myocardial Function in Patients with First Anterior ST-Segment Elevation Myocardial Infarction After Primary Percutaneous Coronary Intervention.Journal of atherosclerosis and thrombosis · 2019Article
- Brachiocephalic artery stenting through the carotid artery: A case report and review of the literature.World journal of clinical cases · 2019Article
- Impact of serum omentin-1 levels on functional prognosis in nondiabetic patients with ischemic stroke.American journal of translational research · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsOmentin-1 was proved to be associated with ischemic stroke clinical functional outcome. It also predicted carotid atherosclerosis among metabolic syndrome subjects and type 2 diabetes patients. Our aim was to examine the association of omentin-1 levels with carotid plaque instability and stenosis degree among ischemic stroke patients.
methodsA total of 173 acute ischemic stroke patients were included in this study. Serum omentin-1 levels were assayed. Carotid ultrasound examinations were performed to evaluate the carotid plaque instability and stenosis degree. Multivariable logistic analyses were used to examine the association of serum omentin-1 levels with carotid plaque instability and stenosis degree.
resultsIschemic stroke patients with unstable carotid plaque had significantly lower levels of serum omentin-1 than patients with stable plaque (53 [40.2-64.1] vs 61.8 [52.4-77.2] ng/ml, P＜0.01). Subjects in the highest tertile of serum omentin-1 levels had a 0.31-fold risk of having unstable plaque compared with those in the lowest tertile (P＜0.05), and its trend test was significant (P for trend=0.03). The integrated discrimination improvement was significantly improved in predicting carotid plaque instability when omentin-1 data was added to the multivariable logistic regression model. No significant association was detected between omentin-1 and moderate-severe carotid stenosis or occlusion.
conclusionsAmong ischemic stroke patients, higher omentin-1 levels were inversely associated with carotid plaque instability, but not associated with moderate-severe carotid stenosis or occlusion. Omentin-1 may represent a biomarker for predicting carotid plaque instability of acute ischemic stroke patients.
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