ReviewProceedings of the Japan Academy. Series B, Physical and biological sciences2017
What do eye movements tell us about patients with neurological disorders? - An introduction to saccade recording in the clinical setting.
Review in Proceedings of the Japan Academy. Series B, Physical and biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 63 citations in OpenAlex.
- Concomitant improvement in anti-saccade success rate and postural instability gait difficulty after rTMS treatment for Parkinson's disease.Scientific reports · 2021Trial
- Patient-Reported Visual Function in Ataxias and Association with Clinical Oculomotor Findings.Cerebellum (London, England) · 2026Article
- Changes in Saccadic Hypometria over Time to Monitor Parkinson's Disease Progression.Pharmaceutical medicine · 2026Observational
- Eye tracking as a digital biomarker in neurodegenerative diseases.Journal of neurology · 2026Review
- Advances in ocular motor and pupil biomarkers for neurological disorders.Brain communications · 2026Review
- Microsaccade Activity During Visuospatial Working Memory in Early-Stage Parkinson's Disease.Journal of eye movement research · 2025Article
- Article
- Augmenting early stroke diagnosis with an eye-tracker.Frontiers in neurology · 2025Article
- Do Miniature Eye Movements Affect Neurofeedback Training Performance? A Combined EEG-Eye Tracking Study.Applied psychophysiology and biofeedback · 2024Article
- Effects of Cervical Spinal Manipulation on Saccadic Eye Movements.Brain sciences · 2024Article
- Cognitive aspects of motor control deteriorate while off treatment following subthalamic nucleus deep brain stimulation surgery in Parkinson's disease.Frontiers in neurology · 2024Article
- Detecting Abnormal Eye Movements in Patients with Neurodegenerative Diseases - Current Insights.Eye and brain · 2024Review
- Distinct eye movement patterns to complex scenes in Alzheimer's disease and Lewy body disease.Frontiers in neuroscience · 2024Article
- Differential eye movement features between Alzheimer's disease patients with and without depressive symptoms.Aging clinical and experimental research · 2023Article
- Significance of clinical symptoms and red flags in early differential diagnosis of Parkinson's disease and atypical Parkinsonian syndromes.Journal of neural transmission (Vienna, Austria : 1996) · 2023Article
- Regularities in vertical saccadic metrics: new insights, and future perspectives.Frontiers in psychology · 2023Article
- A novel tablet-based software for the acquisition and analysis of gaze and eye movement parameters: a preliminary validation study in Parkinson's disease.Frontiers in neurology · 2023Article
- How do patients with Parkinson's disease and cerebellar ataxia read aloud? -Eye-voice coordination in text reading.Frontiers in neuroscience · 2023Article
- Eye movement abnormalities in neurodegenerative langerhans cell histiocytosis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- Effects of different virtual reality technology driven dual-tasking paradigms on posture and saccadic eye movements in healthy older adults.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-invasive and readily implemented in the clinical setting, eye movement studies have been conducted extensively not only in healthy human subjects but also in patients with neurological disorders. The purpose of saccade studies is to "read out" the pathophysiology underlying neurological disorders from the saccade records, referring to known primate physiology. In the current review, we provide an overview of studies in which we attempted to elucidate the patterns of saccade abnormalities in over 250 patients with neurological disorders, including cerebellar ataxia and brainstem pathology due to neurodegenerative disorders, and what they tell about the pathophysiology of patients with neurological disorders. We also discuss how interventions, such as deep brain stimulation, affect saccade performance and provide further insights into the workings of the oculomotor system in humans. Finally, we argue that it is important to understand the functional significance and behavioral correlate of saccade abnormalities in daily life, which could require eye tracking methodologies to be performed in settings similar to daily life.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.