Evidence map›Paper›PMID 29225265›Full record

ArticleInternal medicine (Tokyo, Japan)2018

Posterior Reversible Encephalopathy Syndrome after Lenvatinib Therapy in a Patient with Anaplastic Thyroid Carcinoma.

Yoko Osawa, Rikako Gozawa, Keisuke Koyama, Takeo Nakayama, Tadashi Sagoh, Hiroshi Sunaga

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  5. Neuro-ophthalmic complications of modern anti-cancer drugs.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yoko OsawaDepartment of Otorhinolaryngology, Fukui Red Cross Hospital, Japan.
Rikako GozawaDepartment of Otorhinolaryngology, Fukui Red Cross Hospital, Japan.
Keisuke KoyamaDepartment of Otorhinolaryngology, Fukui Red Cross Hospital, Japan.
Takeo NakayamaDepartment of Neurology, Fukui Red Cross Hospital, Japan.
Tadashi SagohDepartment of Radiology, Fukui Red Cross Hospital, Japan.
Hiroshi SunagaDepartment of Otorhinolaryngology, Fukui Red Cross Hospital, Japan.
Fukui Red Cross Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Posterior reversible encephalopathy syndrome (PRES) is a rare reversible neurological syndrome that causes subcortical vasogenic brain edema and which is associated with the use of target-specific agents. Lenvatinib is a target-specific agent that was recently approved for inoperable thyroid cancer. We herein describe the case of a 66-year-old woman with anaplastic thyroid cancer (ATC) who was treated with lenvatinib and who subsequently developed PRES. The clinical and radiological findings improved after suspending therapy for 1 week, and there was no recurrence with intermittent lower-dose lenvatinib treatment. Lenvatinib may prolong survival in patients with ATC and can be administered intermittently, even after PRES onset.

Indexed as

AgedAntineoplastic AgentsFatal OutcomeFemaleHumansNeoplasm Recurrence, LocalPhenylurea CompoundsPosterior Leukoencephalopathy SyndromeQuinolinesThyroid Carcinoma, AnaplasticThyroid NeoplasmsAntineoplastic AgentslenvatinibPhenylurea CompoundsQuinolinesanaplastic thyroid carcinomalenvatinibposterior reversible encephalopathy syndrometyrosine kinase inhibitor

Identifiers

PMID29225265
PMCPMC5919864
OpenAlexW2773465006

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.