Evidence map›Paper›PMID 29224677›Full record

ReviewBest practice & research. Clinical rheumatology2017

Diagnostic and prognostic tests in systemic lupus erythematosus.

Natalia Vasquez-Canizares, Dawn Wahezi, Chaim Putterman

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Best practice & research. Clinical rheumatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05666336 (Proteomics Combined With Metabolomics Studies on the Efficacy of Telitacicept in Chinese Patients of Systemic Lupus Erythematosus), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05666336 phase4unknown statusnot on this mapstarted 2022, after this paper: background citation

Proteomics Combined With Metabolomics Studies on the Efficacy of Telitacicept in Chinese Patients of Systemic Lupus Erythematosus

TypeinterventionalSponsorFen LiRan2022 to 2024Enrolled30ConditionsSystemic Lupus ErythematosusArmsTelitacicept, Hydroxychloroquine, Prednisone, Methylprednisolone, Cyclophosphamide
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Precipitating anti-dsDNA peptide repertoires in lupus.Clinical and experimental immunology · 2018
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Natalia Vasquez-CanizaresDivision of Pediatric Rheumatology, Children's Hospital at Montefiore and Albert Einstein College of Medicine, Bronx, NY, USA.
Dawn WaheziDivision of Pediatric Rheumatology, Children's Hospital at Montefiore and Albert Einstein College of Medicine, Bronx, NY, USA.
Chaim PuttermanDivision of Rheumatology and Department of Microbiology and Immunology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, USA. Electronic address: chaim.putterman@einstein.yu.edu.
Children's Hospital at Montefiore · USAlbert Einstein College of Medicine · US

Funding

The Renal Pathogenicity of anti-DNA AntibodiesR01AR048692 · NIAMS · YESHIVA UNIVERSITY · PI PUTTERMAN, CHAIM · 2002 to 2013
$4.0M
The role of TWEAK and Fn14 in the Pathogenesis and Treatment of NeuropsychiatricR01AR065594 · NIAMS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI PUTTERMAN, CHAIM · 2014 to 2018
$2.4M
NIAMS NIH HHS R01 AR048692NIAMS NIH HHS R01 AR065594
6 · The paper itself

Abstract

Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease characterized by autoantibodies directed against numerous self-nuclear antigens. Because of the heterogeneous nature of lupus, it has been challenging to identify markers that are sensitive and specific enough for its diagnosis and monitoring. However, with the sequencing of the human genome, rapid development of high-throughput approaches has allowed for a better understanding of the etiopathogenesis of complex diseases, including SLE. Here we present a review of the latest advancements in biomarker discovery during the "omics" era, using these novel technologies, for assisting in the diagnosis and prognosis of patients with SLE.

Indexed as

AutoantibodiesHumansLupus Erythematosus, SystemicPrognosisProteomicsAutoantibodiesBiomarkersEpigeneticsGenomicsLupus nephritisMetabolomicsProteomicsSystemic lupus erythematosusTranscriptomics

Identifiers

PMID29224677
PMCPMC5776716
OpenAlexW2767389767

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.