ArticleAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2018
Impact of Obesity on Modality Longevity, Residual Kidney Function, Peritonitis, and Survival Among Incident Peritoneal Dialysis Patients.
Article in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
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Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.
- Factors influencing catheter-related infections in peritoneal dialysis patients: a meta-analysis.PeerJ · 2025Pooled it
- Influencing factors for residual kidney function in incident peritoneal dialysis patients: a systematic review and meta-analysis.Renal failure · 2023Pooled it
- Long-term glycemic variability and the risk of mortality in diabetic patients receiving peritoneal dialysis.PloS one · 2022Trial
- Long-term dynamic effect of body mass index on adverse cardiovascular outcomes with targeted maximum likelihood estimation method: result from the KNOW-CKD study.Scientific reports · 2026Article
- Obesity and Its Clinical Implications in End-Stage Kidney Disease.Medicina (Kaunas, Lithuania) · 2026Review
- Management of peritoneal dialysis in patients with obesity.Current opinion in nephrology and hypertension · 2026Review
- Dialysis vintage modifies the effect of adsorption-based therapies on protein-bound toxin clearance.Frontiers in cell and developmental biology · 2026Article
- Choosing dialysis modality in patients aged 75 and above with end-stage kidney disease: a multicenter cohort study.Scientific reports · 2025Article
- Peritoneal dialysis in patients with severe obesity: A successful single center experience.Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis · 2025Article
- Impact of obesity on in-hospital outcomes in peritoneal dialysis patients: insights from a nationwide analysis.International urology and nephrology · 2025Article
- Peritoneal dialysis catheter insertion in patients with obesity: a cohort study and single centre approach to increasing uptake.BMC nephrology · 2025Observational
- Hemodialysis-induced renal perfusion decline: unraveling the pathophysiological mechanisms linking intradialytic circulatory stress to residual renal function loss.Frontiers in pharmacology · 2025Article
- Risk factors of peritoneal dialysis-related peritonitis in the Japan Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS).Clinical kidney journal · 2024Article
- Exploring Preconceptions as Barriers to Peritoneal Dialysis Eligibility: A Global Scenario-Based Survey of Kidney Care Physicians.Kidney international reports · 2024Article
- Machine learning algorithms for the prediction of adverse prognosis in patients undergoing peritoneal dialysis.BMC medical informatics and decision making · 2024Article
- The Association Between Serum Vancomycin Level and Clinical Outcome in Patients With Peritoneal Dialysis Associated Peritonitis.Kidney international reports · 2023Article
- Improving rice eating and cooking quality by enhancing endogenous expression of a nitrogen-dependent floral regulator.Plant biotechnology journal · 2023Article
- Clinical impact of catheter insertion for peritoneal dialysis on patient survival and catheter-related complications.Clinical and experimental nephrology · 2023Article
- Plasma vaspin levels and clinical outcome in incident peritoneal dialysis patients.BMC nephrology · 2023Article
- Impact of Weight Gain on the Subsequent Survival of New Peritoneal Dialysis Patients.Kidney diseases (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundThe prevalence of severe obesity, often considered a contraindication to peritoneal dialysis (PD), has increased over time. However, mortality has decreased more rapidly in the PD population than the hemodialysis (HD) population in the United States. The association between obesity and clinical outcomes among patients with end-stage kidney disease remains unclear in the current era. STUDY
designHistorical cohort study. SETTING &
participants15,573 incident PD patients from a large US dialysis organization (2007-2011). PREDICTOR: Body mass index (BMI). OUTCOMES: Modality longevity, residual renal creatinine clearance, peritonitis, and survival.
resultsHigher BMI was significantly associated with shorter time to transfer to HD therapy (P for trend < 0.001), longer time to kidney transplantation (P for trend < 0.001), and, with borderline significance, more frequent peritonitis-related hospitalization (P for trend = 0.05). Compared with lean patients, obese patients had faster declines in residual kidney function (P for trend < 0.001) and consistently achieved lower total Kt/V over time (P for trend < 0.001) despite greater increases in dialysis Kt/V (P for trend < 0.001). There was a U-shaped association between BMI and mortality, with the greatest survival associated with the BMI range of 30 to < 35kg/m LIMITATIONS: Inability to evaluate causal associations. Potential indication bias.
conclusionsWhereas obese PD patients had higher risk for complications than nonobese PD patients, their survival was no worse than matched HD patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.