Evidence map›Paper›PMID 29223466›Full record

ArticleThe international journal of biochemistry & cell biology2018

Long-term pulmonary and cardiovascular morbidities of neonatal hyperoxia exposure in mice.

Renuka T Menon, Amrit Kumar Shrestha, Corey L Reynolds, Roberto Barrios, Binoy Shivanna

Open access · greenAbstract read
In one paragraph

Article in The international journal of biochemistry & cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 33 citations in OpenAlex.

  1. Whole genome transcriptomics reveal distinct atrial versus ventricular responses to neonatal hyperoxia.American journal of physiology. Heart and circulatory physiology · 2025
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  13. EndothelialAntioxidants (Basel, Switzerland) · 2021
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  15. Review
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  17. Interactive and independent effects of early lipopolysaccharide and hyperoxia exposure on developing murine lungs.American journal of physiology. Lung cellular and molecular physiology · 2020
    Article
  18. Article
  19. Early origins of lung disease: towards an interdisciplinary approach.European respiratory review : an official journal of the European Respiratory Society · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Renuka T MenonSection of Neonatology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Amrit Kumar ShresthaSection of Neonatology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Corey L ReynoldsMouse Phenotyping Core, Baylor College of Medicine, Houston, TX, USA.
Roberto BarriosDepartment of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX, USA.
Binoy ShivannaSection of Neonatology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA. Electronic address: shivanna@bcm.edu.
Baylor College of Medicine · USMethodist Hospital · US

Funding

Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Geoffrey A Preidis · 2001 to 2026
$28.3M
Consortium for Broad Based Disease Phenotyping of Knockout MiceU54HG006348 · NHGRI · BAYLOR COLLEGE OF MEDICINE · PI BEAUDET, ARTHUR L., PAYLOR, RICHARD E · 2011 to 2015
$17.0M
Modulation of Neonatal Hyperoxic Lung Injury by the Aryl Hydrocarbon ReceptorK08HD073323 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI SHIVANNA, BINOY · 2013 to 2017
$649k
NHGRI NIH HHS U54 HG006348NICHD NIH HHS K08 HD073323NIDDK NIH HHS P30 DK056338
6 · The paper itself

Abstract

Pulmonary hypertension (PH) frequently occurs in infants with bronchopulmonary dysplasia (BPD), causing increased mortality and right ventricular (RV) dysfunction that persists into adulthood. A first step in developing better therapeutic options is identifying and characterizing an appropriate animal model. Previously, we characterized the short-term morbidities of a model in which C57BL/6J wild-type (WT) mice were exposed to 70% O

Indexed as

Disease Models, AnimalPulmonary CirculationAnimalsAnimals, NewbornAtmosphere Exposure ChambersBronchopulmonary DysplasiaEchocardiographyFeasibility StudiesFemaleHeartHyperoxiaHypertension, PulmonaryLungMagnetic Resonance ImagingMaleMice, Inbred C57BLBronchopulmonary dysplasiaCardiac magnetic resonance imagingEchocardiographyHyperoxiaLong-term morbiditiesPulmonary hypertension

Identifiers

PMID29223466
PMCPMC5745292
OpenAlexW2774135662

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.