ReviewAddictive behaviors2018
The intersection between response inhibition and substance use among adolescents.
Review in Addictive behaviors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- A Multi-Method Meta-Analysis of Neuro-Behavioral Motor Inhibition Outcomes Across Substance-Use Problems and Related Developmental Psychopathological Conditions: A Self-Regulation Approach.Clinical neuropsychiatry · 2026Article
- Neurobehavioral correlates of inhibitory control in youth at-risk for early low-level alcohol use initiation: neuroimaging findings from the ABCD study.Frontiers in psychiatry · 2026Article
- From Pellets to Prizes: Preclinical and Clinical Perspectives on Contingency Management for the Treatment of Substance Use Disorder.Substance abuse and rehabilitation · 2026Review
- Frontal Theta Event-Related Oscillations During a Continuous Performance Test: The Influence of Trauma Type and Fluid Intelligence Polygenic Score.Brain and behavior · 2025Article
- Individuals recently abstinent from methamphetamine show selective cognitive and behavioral differences when compared to age-matched controls.Frontiers in psychiatry · 2025Article
- From individual motivation to substance use initiation: A longitudinal cohort study assessing the associations between reward sensitivity and subsequent risk of substance use initiation among US adolescents.Addictive behaviors · 2025Article
- Adolescent Neurodevelopment Within the Context of Impulsivity and Substance Use.Current addiction reports · 2023Article
- Relationship between Depression and Cognitive Inhibition in Men with Heroin or Methamphetamine Use Disorder in First-Time Mandatory Detoxification.Healthcare (Basel, Switzerland) · 2022Article
- Neurobehavioral maturation of motor response inhibition in adolescence - A narrative review.Neuroscience and biobehavioral reviews · 2022Review
- The neurobiology of childhood trauma, from early physical pain onwards: as relevant as ever in today's fractured world.European journal of psychotraumatology · 2022Review
- Functional Connectivity Predicts Individual Development of Inhibitory Control during Adolescence.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Neural Underpinnings of Social Contextual Influences on Adolescent Risk-Taking.Current addiction reports · 2020Article
- Distraction towards contextual alcohol cues and craving are associated with levels of alcohol use among youth.BMC psychiatry · 2018Article
- Functional reorganization of brain networks from childhood to adolescence: A multi-level approach.International journal of clinical and health psychology : IJCHPArticle
- Multifaceted Quality Improvement Initiative Improves Retention in Treatment for Youth with Opioid Use Disorder.Pediatric quality & safetyArticle
- Exploring Cannabis and Alcohol Co-Use in Adolescents: A Narrative Review of the Evidence.Journal of dual diagnosisReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Problems related to the capacity to successfully engage response inhibition are considered a risk factor for the development of substance use disorders (SUDs), but the evidence has been predominantly cross-sectional. In this commentary, we argue that recent longitudinal studies with multi-modal measures of response inhibition can improve understanding of how response inhibition may intersect with substance use among adolescents. Most Stop-Signal studies suggest that slower response inhibition predicts substance use progressions, with one multi-site study showing greater fronto-parietal activity indicative of risk. Most Go-NoGo studies suggest that blunted activation of prefrontal cortical areas during response inhibition predicts substance use progressions, while commission errors are less effective in identifying adolescents at risk. Studies differ in subject populations, outcome measures, statistical methods, and BOLD response contrasts, which challenge the capacity to compare and generalize findings. We encourage research teams throughout the globe to undertake multi-modal, longitudinal studies to assess brain functioning with large sample sizes, and when possible, before significant substance use potentially obscures interpretation of findings. Systematic review and meta-analysis of this growing literature are also important goals for future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.