Evidence map›Paper›PMID 29222705›Full record

SynthesisJournal of cancer survivorship : research and practice2018

Tai Chi and Qigong for cancer-related symptoms and quality of life: a systematic review and meta-analysis.

Peter M Wayne, M S Lee, J Novakowski, K Osypiuk, J Ligibel, L E Carlson, R Song

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of cancer survivorship : research and practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06243107 (The Effectiveness of Tai-Chi in Cancer Patients Improves Fatigue, Mood, Sleep, Quality of Life and Heart Rate Variability), which is not on this map. Cited by 118 papers, 29 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
118citing papers in PubMed, 29 pooled it
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06243107 nacompletednot on this mapstarted 2019, after this paper: background citation

The Effectiveness of Tai-Chi in Cancer Patients Improves Fatigue, Mood, Sleep, Quality of Life and Heart Rate Variability

TypeinterventionalSponsorChang Gung Memorial HospitalRan2019 to 2022Enrolled68ConditionsCancerArmsTai-chi
3 · Its place in the literature

Who cites it

118 citing papers in PubMed, 29 syntheses or guidelines pooled it, 239 citations in OpenAlex.

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  5. Mind-body interventions for cancer-related dyspnoea: a systematic review and meta-analysis of randomised controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
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  7. Stress reduction through taiji: a systematic review and meta-analysis.BMC complementary medicine and therapies · 2024
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  10. Meditative movement for breathlessness in advanced COPD or cancer: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2023
    Pooled it
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  12. Is physical activity effective against cancer-related fatigue in lung cancer patients? An umbrella review of systematic reviews and meta-analyses.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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  16. Cancer-related fatigue in patients treated with mistletoe extracts: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Pooled it
  17. Do Patients with Prostate Cancer Benefit from Exercise Interventions? A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022
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58 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

Peter M WayneOsher Center for Integrative Medicine, Harvard Medical School and Brigham and Women's Hospital, 900 Commonwealth Avenue, 3rd floor, Boston, MA, 02215, USA. pwayne@partners.org.
M S LeeClinical Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.
J NovakowskiOsher Center for Integrative Medicine, Harvard Medical School and Brigham and Women's Hospital, 900 Commonwealth Avenue, 3rd floor, Boston, MA, 02215, USA.
K OsypiukOsher Center for Integrative Medicine, Harvard Medical School and Brigham and Women's Hospital, 900 Commonwealth Avenue, 3rd floor, Boston, MA, 02215, USA.
J LigibelZakim Center for Integrative Therapies and Healthy Living, Dana Farber Cancer Institute, Boston, MA, USA.
L E CarlsonCumming School of Medicine, University of Calgary, Calgary, AB, Canada.
R SongCollege of Nursing, Chungnam National University, Daejeon, Republic of Korea.
Brigham and Women's Hospital · USChungnam National University · KRDana-Farber Cancer Institute · USHarvard University · USKorea Institute of Oriental Medicine · KRUniversity of Calgary · CA

Funding

Mentoring and research in mind-body and integrative therapiesK24AT009282 · NCCIH · BRIGHAM AND WOMEN'S HOSPITAL · PI WAYNE, PETER MICHAEL · 2017 to 2021
$834k
NCCIH NIH HHS K24 AT009282
6 · The paper itself

Abstract

purposeThis study aims to summarize and critically evaluate the effects of Tai Chi and Qigong (TCQ) mind-body exercises on symptoms and quality of life (QOL) in cancer survivors.

methodsA systematic search in four electronic databases targeted randomized and non-randomized clinical studies evaluating TCQ for fatigue, sleep difficulty, depression, pain, and QOL in cancer patients, published through August 2016. Meta-analysis was used to estimate effect sizes (ES, Hedges' g) and publication bias for randomized controlled trials (RCTs). Methodological bias in RCTs was assessed.

resultsOur search identified 22 studies, including 15 RCTs that evaluated 1283 participants in total, 75% women. RCTs evaluated breast (n = 7), prostate (n = 2), lymphoma (n = 1), lung (n = 1), or combined (n = 4) cancers. RCT comparison groups included active intervention (n = 7), usual care (n = 5), or both (n = 3). Duration of TCQ training ranged from 3 to 12 weeks. Methodological bias was low in 12 studies and high in 3 studies. TCQ was associated with significant improvement in fatigue (ES = - 0.53, p < 0.001), sleep difficulty (ES = - 0.49, p = 0.018), depression (ES = - 0.27, p = 0.001), and overall QOL (ES = 0.33, p = 0.004); a statistically non-significant trend was observed for pain (ES = - 0.38, p = 0.136). Random effects models were used for meta-analysis based on Q test and I

conclusionsLarger and methodologically sound trials with longer follow-up periods and appropriate comparison groups are needed before definitive conclusions can be drawn, and cancer- and symptom-specific recommendations can be made. IMPLICATIONS FOR CANCER SURVIVORS: TCQ shows promise in addressing cancer-related symptoms and QOL in cancer survivors.

Indexed as

QigongQuality of LifeTai JiCancer SurvivorsDatabases, FactualDepressionExerciseExercise TherapyFatigueFemaleHumansMaleNeoplasmsRandomized Controlled Trials as TopicCancerFatigueMeta-analysisQigongQuality of lifeTai Chi

Identifiers

PMID29222705
PMCPMC5958892
OpenAlexW2772914537

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.