Evidence map›Paper›PMID 29222677›Full record

ArticleEuropean radiology2018

Diagnostic evaluation of magnetization transfer and diffusion kurtosis imaging for prostate cancer detection in a re-biopsy population.

Tristan Barrett, Mary McLean, Andrew N Priest, Edward M Lawrence, Andrew J Patterson, Brendan C Koo, Ilse Patterson, Anne Y Warren, Andrew Doble, Vincent J Gnanapragasam and 2 more

Open access · hybridAbstract readEvaluation Study
In one paragraph

Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Biochemical and microenvironmental characterization of the disc-vertebra complex in non-specific low back pain using non-fat-saturation multi-slice CEST MRI.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  4. Prognostic features of biochemical recurrence of prostate cancer following radical prostatectomy based on diffusion kurtosis imaging.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Tristan BarrettDepartment of Radiology, University of Cambridge, Cambridge, UK. tb507@medschl.cam.ac.uk.
Mary McLeanCRUK Cambridge Institute, Cambridge, UK.
Andrew N PriestDepartment of Radiology, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK.
Edward M LawrenceDepartment of Radiology, University of Cambridge, Cambridge, UK.
Andrew J PattersonDepartment of Radiology, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK.
Brendan C KooDepartment of Radiology, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK.
Ilse PattersonDepartment of Radiology, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK.
Anne Y WarrenCamPARI Clinic, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK.
Andrew DobleCamPARI Clinic, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK.
Vincent J GnanapragasamCamPARI Clinic, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK.
Christof KastnerCamPARI Clinic, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK.
Ferdia A GallagherDepartment of Radiology, University of Cambridge, Cambridge, UK.
Addenbrooke's Hospital · GBUniversity of Cambridge · GBAlzheimer’s Research UK · GBMemorial Sloan Kettering Cancer Center · US

Funding

Cancer Research UK 11562Cancer Research UK 16628
6 · The paper itself

Abstract

objectiveTo evaluate diffusion kurtosis imaging (DKI) and magnetisation transfer imaging (MTI) compared to standard MRI for prostate cancer assessment in a re-biopsy population.

methodsThirty-patients were imaged at 3 T including DKI (K

resultsTwenty patients had ≥ 1 core positive for cancer in a total of 26 MRI targets (Gleason 3+3 in 8, 3+4 in 12, ≥ 4+3 in 6): 13 peripheral (PZ) and 13 transition zone (TZ). The apparent diffusion coefficient (ADC) and D

conclusionADC, D KEY POINTS: • MTR was significantly higher in PZ and TZ tumours versus normal tissue • K

Indexed as

AgedDiffusion Magnetic Resonance ImagingDiffusion Tensor ImagingHumansImage-Guided BiopsyImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesProstatic NeoplasmsRetreatmentROC CurveDiffusion kurtosis imagingDiffusion-weighted imagingMagnetisation transfer imagingMRIProstate

Identifiers

PMID29222677
PMCPMC6028858
OpenAlexW2772772114

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.