Evidence map›Paper›PMID 29222645›Full record

ReviewCellular and molecular life sciences : CMLS2018

Role of the microenvironment in myeloid malignancies.

Marie Goulard, Christine Dosquet, Dominique Bonnet

Open access · hybridAbstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
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  13. Bone Marrow Microenvironment Involvement in t-MN: Focus on Mesenchymal Stem Cells.Mediterranean journal of hematology and infectious diseases · 2023
    Review
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  15. Article
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  17. Myelodysplastic Syndromes and Metabolism.International journal of molecular sciences · 2021
    Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Marie GoulardINSERM, UMRS1131-Paris Diderot University, Saint Louis Hospital, Paris, France.
Christine DosquetINSERM, UMRS1131-Paris Diderot University, Saint Louis Hospital, Paris, France.
Dominique BonnetHaematopoietic Stem Cell Laboratory, The Francis Crick Institute, 1, Midland Road, London, NW1 1AT, UK. dominique.bonnet@crick.ac.uk.
Délégation Paris 7 · FRThe Francis Crick Institute · GBUniversité Paris Cité · FR

Funding

Cancer Research UK 15692Cancer Research UK FC001045Medical Research Council FC0010045Wellcome Trust FC001045
6 · The paper itself

Abstract

The bone marrow microenvironment (BMM) regulates the fate of hematopoietic stem cells (HSCs) in homeostatic and pathologic conditions. In myeloid malignancies, new insights into the role of the BMM and its cellular and molecular actors in the progression of the diseases have started to emerge. In this review, we will focus on describing the major players of the HSC niche and the role of the altered niche function in myeloid malignancies, more specifically focusing on the mesenchymal stroma cell compartment.

Indexed as

AnimalsCellular MicroenvironmentHematopoietic Stem CellsHomeostasisHumansMyeloid CellsNeoplasmsNeoplastic Stem CellsStem Cell NicheBone marrow nicheLeukemic-initiating cellsMesenchymal stroma cellsMyeloid malignancies

Identifiers

PMID29222645
PMCPMC5852194
OpenAlexW2775219485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.